Book Excerpt from Future Science: Essays From the Cutting Edge

In an essay entitled "Molecular Cut and Paste: The New Generation of Biological Tools," virologist William McEwan envisions a future where viruses are reprogrammed to become the workhorses of science and medicine.

Written byWilliam McEwan
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VINTAGE, AUGUST 2011

This afternoon I received in the post a slim FedEx envelope containing four small vials of DNA. The DNA had been synthesized according to my instructions in under three weeks, at a cost of 39 U.S. cents per base pair (the rungs adenine-thymine or guanine-cytosine in the DNA ladder). The 10 micrograms I ordered are dried, flaky, and barely visible to the naked eye, yet once I have restored them in water and made an RNA copy of this template, they will encode a virus I have designed.

My virus will be self-replicating, but only in certain tissue-culture cells; it will cause any cell it infects to glow bright green and will serve as a research tool to help me answer questions concerning antiviral immunity. ...

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