Brain Cells Self-Amplify

A certain type of neural precursor does it all—replaces itself, differentiates into specialized brain cells, and multiplies into more stem-cell-like cells.

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Carefully watching individual brain cells called radial glia-like (RGL) cells in the brains of mice, researchers have identified a new capability—self-amplification. The study, published last month in Cell, provides evidence that these cells can divide to create two of themselves in addition to generating both mature neurons and the surrounding support cells known as glia.

"Now we know they don't just maintain their numbers, or go down in number, but that stem cells can amplify," neuroscientist Hongjun Song, director of the Stem Cell Program in the Institute for Cell Engineering at the Johns Hopkins University School of Medicine and coauthor of the study, said in a press release. "If we can somehow cash in on this newly discovered property of stem cells in the brain, ...

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Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
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