Brain Cells Self-Amplify

A certain type of neural precursor does it all—replaces itself, differentiates into specialized brain cells, and multiplies into more stem-cell-like cells.

Written byJef Akst
| 1 min read

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Carefully watching individual brain cells called radial glia-like (RGL) cells in the brains of mice, researchers have identified a new capability—self-amplification. The study, published last month in Cell, provides evidence that these cells can divide to create two of themselves in addition to generating both mature neurons and the surrounding support cells known as glia.

"Now we know they don't just maintain their numbers, or go down in number, but that stem cells can amplify," neuroscientist Hongjun Song, director of the Stem Cell Program in the Institute for Cell Engineering at the Johns Hopkins University School of Medicine and coauthor of the study, said in a press release. "If we can somehow cash in on this newly discovered property of stem cells in the brain, ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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