Building Bigger Beefsteaks

Understanding the genetics of stem cell population maintenance in plants producing jumbo tomatoes could help scientists generate more-massive fruits.

Written byTracy Vence
| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

UGLY FRUIT: Some tomato varieties, such as this one with mutations in the lc and fas genes, grow interestingly shaped fruit.ESTHER VAN DER KNAAP

He doesn’t garden at home, but plant geneticist Zachary Lippman does cultivate his own small kitchen crop of grape tomatoes among the five acres of the fruit grown for research in Cold Spring Harbor Laboratory’s fields each year. Having studied tomatoes for nearly two decades, Lippman, an associate professor at Cold Spring Harbor, knows the fruit well. He’s partial to plants that produce smaller tomatoes, because they “grow like weeds” compared to the many hefty varieties commonly found at farmers’ markets.

Tomatoes weren’t always so beefy. Much like Lippman’s grape-tomato plants, wild ancestors of the domesticated crop (Solanum lycopersicum) bore berry-size fruit—a far cry from the SteakHouse variety of up-to-three-pounders currently sold by seed company Burpee.

“Since domestication, diversity at the genome level has been ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies