Ribbon weed meadow in Shark Bay, Western Australia
World’s Largest Organism Discovered Underwater
Off the western Australian coast, in Shark Bay, a field of seagrass big enough to cover Washington, DC, has flourished for more than four millennia, a new study finds.
World’s Largest Organism Discovered Underwater
World’s Largest Organism Discovered Underwater

Off the western Australian coast, in Shark Bay, a field of seagrass big enough to cover Washington, DC, has flourished for more than four millennia, a new study finds.

Off the western Australian coast, in Shark Bay, a field of seagrass big enough to cover Washington, DC, has flourished for more than four millennia, a new study finds.

mutations
Illustration of light blue speckled DNA helix on a dark background
Study Nearly Doubles Known Cancer-Linked Mutational Signatures
Jef Akst | Apr 22, 2022
Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.
An orange CRISPR Cas 9 enzyme cutting DNA
CRISPR-Based Treatment Successfully Lowers Toxic Protein Levels
Natalia Mesa | Mar 2, 2022
A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.
Challenges and Applications
Combinatorial Single Cell CRISPR Screens: Challenges and Applications
The Scientist Creative Services Team in collaboration with 10x Genomics
An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications.
Microscopy image showing patches of magenta and green
Three Autism-Linked Genes Converge on Tweaks to Cells’ Timing
Angie Voyles Askham, Spectrum | Feb 3, 2022
The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.
Man with glasses wearing yellow long sleeve shirt sits at a desk, surrounded by stacks of paper
Stephen Warren, Icon of Fragile X Research, Dies at 67
Lisa Winter | Sep 21, 2021
He famously identified the genetic mutation that causes the condition in 1991.
tube of blood labeled positive for COVID-19 Mu variant
What We Know About Mu, the WHO’s Latest Variant of Interest
Christie Wilcox | Sep 7, 2021
The SARS-CoV-2 variant was first detected in January, but its rising prevalence and potential resistance to vaccines has garnered it special attention from the World Health Organization.
artistic drawing of neuron filled with tau proteins
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.
An artistic rendering of blue neurons against a white background
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Amanda Heidt | Aug 12, 2021
The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
No Transgenerational Effects of Chernobyl Radiation Found
Abby Olena | Apr 22, 2021
The genomes of the children of people exposed to fallout from the Chernobyl nuclear accident appear to carry no trace of the incident.
Variant Found in Brazil Could Evade Immunity from Past Infection
Lisa Winter | Mar 2, 2021
The P.1 variant, which has also been detected in five US states, could be responsible for cases of reinfection, according to a preprint.
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Jef Akst | Mar 1, 2021
Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.
SARS-CoV-2 with Genomic Deletions Escapes an Antibody
Abby Olena | Feb 16, 2021
Researchers identify deletions in the N-terminal domain of the spike protein that allow the coronavirus to avoid antibody neutralization and that may contribute to the emergence of new variants.
New SARS-CoV-2 Variant Could Evade Antibodies
Lisa Winter | Jan 22, 2021
A preprint casts doubt on vaccine effectiveness in light of certain mutations in the 501Y.V2 variant that emerged from South Africa.
Skin Sheltered from Sunlight Still Gathers UV-Linked Mutations
Abby Olena | Jan 14, 2021
Whole-genome sequencing reveals a wide range of UV-induced DNA changes in human skin cells, and lighter skin collects more mutations, sometimes to “sky high” levels.
Identical Twins Accumulate Genetic Differences in the Womb
Catherine Offord | Jan 7, 2021
DNA replication errors during cell division cause monozygotic twins to diverge from each other even during the earliest stages of development, a new study finds.
gene, CRISPR, CRISPR-Cas9, gene editing, human embryo, chromosome, mutation, deletion
CRISPR Gene Editing Prompts Chaos in DNA of Human Embryos
Amanda Heidt | Jun 26, 2020
Three studies identify unintended consequences of gene editing in human embryos, including large deletions and reshuffling of DNA.
Relatively Stable SARS-CoV-2 Genome Is Good News for a Vaccine
Amy Schleunes | Mar 25, 2020
The small number of genetic differences between the original strain of the novel coronavirus from Wuhan and those currently circulating in the US population indicates that a vaccine may likely offer lasting immunity.
Human Mutation Rates Steady Across Groups—Except in the Amish
Abby Olena | Jan 29, 2020
Researchers determined that the incidence of new genetic mutations is comparable in people of different ancestries, but lower in Amish people.
Cancer Cells Increase DNA Mutations to Evade Treatment
Abby Olena | Nov 7, 2019
Colorectal tumor cells limit their DNA repair in response to a targeted therapy, giving them a greater chance to develop resistance to the drug.