Image of the Day: Mouse Tails
Carolyn Wilke | Jan 24, 2019
Genetic mutations create lab mice with unusually long and short tails.
Infographic: Treating Duchenne Muscular Dystrophy with CRISPR
Sandeep Ravindran | Aug 30, 2018
The disease is caused by mutations in a single gene. Can gene editing fix the problem?
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Shawna Williams | May 1, 2018
The UCLA geneticist examines how defects in a histone protein lead to symptoms throughout the body.
Rare Disease Geneticist: A Profile of Uta Francke
Anna Azvolinsky | May 1, 2018
The Stanford University human geneticist identified the genes and genomic abnormalities underlying numerous rare diseases, including Rett syndrome, and advanced the field of molecular diagnostics.
Exome Sequencing Helps Crack Rare Disease Diagnosis
Amanda B. Keener | May 1, 2018
Clinical analyses of patients’ gene sequences are helping to provide answers where none were available before.
Scientists Reverse Their Controversial Findings of CRISPR's Off-Target Effects
Diana Kwon | Mar 28, 2018
Last year, researchers claimed the gene-editing method had accuracy issues, but a new whole-genome sequencing analysis by the same team finds otherwise.
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.
First Direct-to-Consumer BRCA Test Authorized by FDA
Kerry Grens | Mar 6, 2018
The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.
Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
Ruth Williams | Dec 7, 2017
Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.