Stephen Warren, Icon of Fragile X Research, Dies at 67
Stephen Warren, Icon of Fragile X Research, Dies at 67
He famously identified the genetic mutation that causes the condition in 1991.
Stephen Warren, Icon of Fragile X Research, Dies at 67
Stephen Warren, Icon of Fragile X Research, Dies at 67

He famously identified the genetic mutation that causes the condition in 1991.

He famously identified the genetic mutation that causes the condition in 1991.

mutations
What We Know About Mu, the WHO’s Latest Variant of Interest
What We Know About Mu, the WHO’s Latest Variant of Interest
Christie Wilcox | Sep 7, 2021
The SARS-CoV-2 variant was first detected in January, but its rising prevalence and potential resistance to vaccines has garnered it special attention from the World Health Organization.
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Amanda Heidt | Aug 12, 2021
The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
No Transgenerational Effects of Chernobyl Radiation Found
No Transgenerational Effects of Chernobyl Radiation Found
Abby Olena | Apr 22, 2021
The genomes of the children of people exposed to fallout from the Chernobyl nuclear accident appear to carry no trace of the incident.
Variant Found in Brazil Could Evade Immunity from Past Infection
Variant Found in Brazil Could Evade Immunity from Past Infection
Lisa Winter | Mar 2, 2021
The P.1 variant, which has also been detected in five US states, could be responsible for cases of reinfection, according to a preprint.
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Jef Akst | Mar 1, 2021
Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.
SARS-CoV-2 with Genomic Deletions Escapes an Antibody
SARS-CoV-2 with Genomic Deletions Escapes an Antibody
Abby Olena | Feb 16, 2021
Researchers identify deletions in the N-terminal domain of the spike protein that allow the coronavirus to avoid antibody neutralization and that may contribute to the emergence of new variants.
New SARS-CoV-2 Variant Could Evade Antibodies
New SARS-CoV-2 Variant Could Evade Antibodies
Lisa Winter | Jan 22, 2021
A preprint casts doubt on vaccine effectiveness in light of certain mutations in the 501Y.V2 variant that emerged from South Africa.
Skin Sheltered from Sunlight Still Gathers UV-Linked Mutations
Skin Sheltered from Sunlight Still Gathers UV-Linked Mutations
Abby Olena | Jan 14, 2021
Whole-genome sequencing reveals a wide range of UV-induced DNA changes in human skin cells, and lighter skin collects more mutations, sometimes to “sky high” levels.
Identical Twins Accumulate Genetic Differences in the Womb
Identical Twins Accumulate Genetic Differences in the Womb
Catherine Offord | Jan 7, 2021
DNA replication errors during cell division cause monozygotic twins to diverge from each other even during the earliest stages of development, a new study finds.
CRISPR Gene Editing Prompts Chaos in DNA of Human Embryos
CRISPR Gene Editing Prompts Chaos in DNA of Human Embryos
Amanda Heidt | Jun 26, 2020
Three studies identify unintended consequences of gene editing in human embryos, including large deletions and reshuffling of DNA.
Relatively Stable SARS-CoV-2 Genome Is Good News for a Vaccine
Relatively Stable SARS-CoV-2 Genome Is Good News for a Vaccine
Amy Schleunes | Mar 25, 2020
The small number of genetic differences between the original strain of the novel coronavirus from Wuhan and those currently circulating in the US population indicates that a vaccine may likely offer lasting immunity.
Human Mutation Rates Steady Across Groups—Except in the Amish
Human Mutation Rates Steady Across Groups—Except in the Amish
Abby Olena | Jan 29, 2020
Researchers determined that the incidence of new genetic mutations is comparable in people of different ancestries, but lower in Amish people.
Cancer Cells Increase DNA Mutations to Evade Treatment
Cancer Cells Increase DNA Mutations to Evade Treatment
Abby Olena | Nov 7, 2019
Colorectal tumor cells limit their DNA repair in response to a targeted therapy, giving them a greater chance to develop resistance to the drug.
Image of the Day: Cellular Breakdown
Image of the Day: Cellular Breakdown
Carolyn Wilke | Jan 31, 2019
Autophagy may keep cell division in check to help protect against cancer-causing DNA damage.
Image of the Day: Mouse Tails
Image of the Day: Mouse Tails
Carolyn Wilke | Jan 24, 2019
Genetic mutations create lab mice with unusually long and short tails.
Infographic: Treating Duchenne Muscular Dystrophy with CRISPR
Infographic: Treating Duchenne Muscular Dystrophy with CRISPR
Sandeep Ravindran | Aug 30, 2018
The disease is caused by mutations in a single gene. Can gene editing fix the problem?
Rare Disease Geneticist: A Profile of Uta Francke
Rare Disease Geneticist: A Profile of Uta Francke
Anna Azvolinsky | May 1, 2018
The Stanford University human geneticist identified the genes and genomic abnormalities underlying numerous rare diseases, including Rett  syndrome, and advanced the field of molecular diagnostics. 
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Shawna Williams | May 1, 2018
The UCLA geneticist examines how defects in a histone protein lead to symptoms throughout the body.