Dengue Vaccine Program Halted Over Safety Issues

The drug may worsen future infections for people who haven't already been exposed to the virus.

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syringe and vialsISTOCK, ESBEN_HThe Philippines has halted a dengue immunization program after the drug’s maker announced last week that its effectiveness is different in people who have not previously been exposed to the virus than in those who have, the Independent reports. The public health effort, begun last year, had vaccinated about 733,000 children at a cost of USD $70 million, according to STAT.

Two studies have suggested that for children who haven’t been exposed to dengue before vaccination, Dengvaxia, the drug made by France-based pharmaceutical company Sanofi, can actually increase the likelihood of hospitalization for the disease, STAT notes. “I do not believe . . . anybody should be going forward using this vaccine without testing the individual recipient to be sure they’re already seropositive. Because that’s the group that can benefit from this vaccine,” former U.S. Army scientist Scott Halstead told the outlet last year.

Harry Roque, a spokesperson for the Philippine president, said in a statement that the country’s health department is now closely monitoring people who received the vaccine. “We will leave no stone unturned in making those responsible for this shameless public health scam ...

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Meet the Author

  • Shawna Williams

    Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor's degree in biochemistry from Colorado College and a graduate certificate and science communication from the University of California, Santa Cruz.
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