A Challenge Trial for COVID-19 Would Not Be the First of Its Kind
A Challenge Trial for COVID-19 Would Not Be the First of Its Kind
Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.
A Challenge Trial for COVID-19 Would Not Be the First of Its Kind
A Challenge Trial for COVID-19 Would Not Be the First of Its Kind

Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.

Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.

dengue infection
For the Greater Good: A Profile of Eva Harris
For the Greater Good: A Profile of Eva Harris
Diana Kwon | Jul 13, 2020
Through groundbreaking studies on dengue and efforts to build scientific infrastructure in Latin America, the University of California, Berkeley, professor has bridged research with its benefits to society.
Dengue Cases Drop After Bacteria-Infected Mosquitoes Released
Dengue Cases Drop After Bacteria-Infected Mosquitoes Released
Emily Makowski | Nov 22, 2019
Aedes aegypti infected with Wolbachia—which inhibit transmission of the dengue virus from insect to human—were deployed in Indonesia, Vietnam, Brazil, and Australia.
Past Dengue Infection Appears to Protect Children from Zika Symptoms
Past Dengue Infection Appears to Protect Children from Zika Symptoms
Carolyn Wilke | Jan 23, 2019
Children were 38 percent less likely to show signs of Zika infection if they had previously had dengue.
Antibiotics Increase Mouse Susceptibility to Dengue, West Nile, and Zika
Antibiotics Increase Mouse Susceptibility to Dengue, West Nile, and Zika
Shawna Williams | Mar 27, 2018
The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.
Dengue Vaccine Program Halted Over Safety Issues
Dengue Vaccine Program Halted Over Safety Issues
Shawna Williams | Dec 5, 2017
The drug may worsen future infections for people who haven't already been exposed to the virus.
Dengue Infection Impairs Immune Defense Against Zika
Dengue Infection Impairs Immune Defense Against Zika
Catherine Offord | Aug 18, 2017
A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anna Azvolinsky | Mar 30, 2017
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.
Zika and Dengue Immunity: A Complex Relationship
Zika and Dengue Immunity: A Complex Relationship
Amanda B. Keener | Jun 28, 2016
Researchers examine the blood of people infected with dengue virus, finding a few Zika-neutralizing antibodies among mostly enhancing ones.
Dengue Antibodies Enhance Zika Infection?
Dengue Antibodies Enhance Zika Infection?
Tanya Lewis | Apr 28, 2016
Previous flavivirus infection could help explain the severity of symptoms in some people infected during the ongoing Zika outbreak, researchers report.