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A person in a white shirt activates a nasal spray
Oxford-AstraZeneca Nasal COVID-19 Vaccine Falters in Clinical Trial
Researchers say they’re abandoning the project in its current form—one of several that aims to induce what’s known as mucosal immunity against SARS-CoV-2.
Oxford-AstraZeneca Nasal COVID-19 Vaccine Falters in Clinical Trial
Oxford-AstraZeneca Nasal COVID-19 Vaccine Falters in Clinical Trial

Researchers say they’re abandoning the project in its current form—one of several that aims to induce what’s known as mucosal immunity against SARS-CoV-2.

Researchers say they’re abandoning the project in its current form—one of several that aims to induce what’s known as mucosal immunity against SARS-CoV-2.

immunization

Small vaccine bottles on a conveyer belt
Pfizer and Moderna COVID-19 Omicron Boosters Get OK from the FDA
Catherine Offord | Aug 31, 2022 | 3 min read
The immunizations are designed to target the latest Omicron subvariants, and are only authorized for people who have already received their primary vaccinations.
Spraying spray bottle
Nasal Vaccines Are Commercially High Risk, Perhaps High Reward
Jef Akst | Jun 13, 2022 | 10+ min read
Dozens of intranasally delivered vaccines targeting SARS-CoV-2 are in development. Could they pave the way for widespread nasal vaccination in the future?
stained microscope image of a germinal center inside a lymph node
Booster Is Best in the Same Limb as Initial Vaccine: Mouse Study
Alejandra Manjarrez, PhD | May 6, 2022 | 4 min read
Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.
In one of the only known photos of Abraham Lincoln taken on the day of the Gettysburg Address, Lincoln can be seen seated, hatless, just below and to the right of the flag. Lincoln began developing symptoms of smallpox on the train home to Washington, DC.
Presidential Pox, 1863
Annie Melchor | Dec 1, 2021 | 3 min read
Researchers continue to debate whether US President Abraham Lincoln was coming down with smallpox as he delivered his famous Gettysburg Address, and if he had been immunized.
a man in a white t-shirt and face mask receives a bandage on his arm from a clinician wearing blue gloves and a plastic face shield
COVID-19 Vaccines Work in People with Cancer: Study
Marcus A. Banks | Jun 25, 2021 | 4 min read
Moderna’s, Pfizer’s, and Johnson & Johnson’s shots all offered protection against the virus regardless of cancer type, although slightly less so in people with blood cancer.
Woman holding a CDC COVID-19 vaccination card with both hands.
COVID-19 mRNA Vaccines Appear Effective Against Multiple Variants
Lisa Winter | May 6, 2021 | 2 min read
Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.
Pink background with menstrual products off to the right
No Proof COVID-19 Vaccine Affects Menstruation or Fertility
Lisa Winter | Apr 27, 2021 | 2 min read
Following vaccination, some women claim their periods have changed, leading to rumors about how the shots affect recipients’ reproductive systems, and even others’ by proxy.  
Blood Clots a Very Rare Side Effect of AstraZeneca Vaccine: EMA
Catherine Offord | Apr 8, 2021 | 2 min read
The European Medicines Agency emphasizes that the benefits of the jab in protecting against COVID-19 still far outweigh the risks.
Scientists Reverse Engineer mRNA Sequence of Moderna Vaccine
Lisa Winter | Apr 6, 2021 | 2 min read
Stanford University researchers determined the code from spare drops in discarded vials of the COVID-19 vaccine and published it on GitHub.
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AstraZeneca’s COVID-19 Shot Completely Prevented Severe Disease
Kerry Grens | Mar 22, 2021 | 2 min read
The vaccine was 79 percent effective at blocking symptomatic infections, according to data from a Phase 3 trial in the US, Chile, and Peru. A US safety oversight board says the data might be incomplete.
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COVID-19 Hospitalizations Tank a Month After Vaccines Roll Out
Asher Jones | Feb 23, 2021 | 2 min read
Two preliminary reports from the UK provide real-world evidence in support of the Pfizer/BioNTech and Oxford-AstraZeneca vaccines.
New SARS-CoV-2 Variant Could Evade Antibodies
Lisa Winter | Jan 22, 2021 | 3 min read
A preprint casts doubt on vaccine effectiveness in light of certain mutations in the 501Y.V2 variant that emerged from South Africa.
Patients Reinfected with Coronavirus in Hong Kong, Europe
Lisa Winter | Aug 25, 2020 | 2 min read
So far, there are three patients known to have been infected with SARS-CoV-2 twice, and in at least one case the second time around was asymptomatic.
Bioethicists Criticize WHO’s Malaria Vaccine Trial
Lisa Winter | Feb 28, 2020 | 3 min read
The study, conducted in Malawi, Kenya, and Ghana, did not obtain informed consent from each parent whose child participated, but rather considered consent “implied” because of the particular experimental design.
50 Children Dead from Measles Outbreak in Samoa 
Emily Makowski | Dec 2, 2019 | 1 min read
The public health emergency has spurred a mass vaccination campaign.
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Study Finds Low Trust in Vaccines in Europe
Chia-Yi Hou | Jun 19, 2019 | 2 min read
Just half of respondents in Eastern Europe agree that vaccines are safe.
A bottle labelled "malaria vaccine" with a syringe
Distribution of World’s First Malaria Vaccine Begins
Shawna Williams | Apr 23, 2019 | 1 min read
The World Health Organization and its partners will test the public health effect of immunization in parts of Malawi, Ghana, and Kenya.
Measles Cases Rise in Outbreaks in Ukraine, Philippines
Kerry Grens | Feb 14, 2019 | 2 min read
The World Health Organization reports that a number of countries are experiencing “sizeable” numbers of the infection due to a failure to vaccinate.
Questions Raised About Pertussis Reemergence
Abby Olena, PhD | Dec 20, 2018 | 4 min read
Scientists debate why the number of whooping cough cases is up, and whether the effectiveness of a vaccine introduced within the last two decades is to blame.
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