Molecular Devices, a leader in bioanalytical systems for drug discovery, life science research, and bioassay development, today announced the launch of the Digidata® 1550A Low-Noise Data Acquisition System plus HumSilencer™ noise cancelling technology for the analog-to-digital conversion of biological signals measured in electrophysiology experiments. The Digidata 1550A is the first digitizer with built-in adaptive noise cancellation technology, called the HumSilencer, which provides single-click elimination of the 50 and 60 Hz line-frequency noise that can severely impair analysis of biological signals.
The dysfunction of ion channels, which regulate the flow of ions in and out of cells, is implicated in numerous neurological and cardiovascular diseases. Measuring ionic current through the channels requires a patch clamp system sensitive enough to record a small signal—on the order of pico to nano amps (10-12 to 10-9 A)—and that is not susceptible to electrical noise in the laboratory environment. Improperly shielded or grounded electrical devices ...