Dogs’ Friendly Demeanor Written in Their DNA

Researchers pinpoint the genes that make pooches so dang affable.

Written byBob Grant
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

A socialized wolf briefly greeting an unfamiliar experimenter.IMAGE: MONTY SLOANThe key to dogs’ transformation from wild wolves into faithful canine companions may reside in a handful of genes, according to a new study. The authors of the paper, published yesterday (July 19) in Science Advances, suggest that a couple genes in the same region of a single chromosome might have played a role in the extreme sociability that likely attended the domestication of wolves tens of thousands of years ago.

These genes, GTF2I and GTF2IRD1, also play a role in a human disease, Williams-Beuren syndrome, marked by hyper sociability.

“It is great to see initial genetic evidence supporting the self-domestication hypothesis or ‘survival of the friendliest,’” Duke University evolutionary anthropologist Brian Hare, who was not involved in the study, tells Science News. “This is another piece of the puzzle suggesting that humans did not create dogs intentionally, but instead wolves that were friendliest toward humans were at an evolutionary advantage as our two species began to interact.”

Princeton University evolutionary biologist Bridgett vonHoldt and her coauthors studied the behavior of 16 dogs and eight socialized, captive grey wolves, finding that when faced with a cognitively challenging task, dogs spent more time looking at and interacting ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

    View Full Profile
Share
December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

MilliporeSigma purple logo
Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment 

Cellecta logo
An image of a DNA sequencing spectrum with a radial blur filter applied.

A Comprehensive Guide to Next-Generation Sequencing

Integra Logo

Products

brandtech logo

BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS) 

Top Innovations 2026 Contest Image

Enter Our 2026 Top Innovations Contest

Biotium Logo

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS