Drop Statistical Significance, Scientists Say

In service of an arbitrary threshold, p-values often lead researchers to make poorly supported claims and ignore interesting but insignificant results, scientists argue.

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

ABOVE: © ISTOCK.COM,
SANJERI

The current way many researchers apply p-values to draw conclusions on statistical significance is incorrect and unhelpful, three scientists argue in a Nature commentary published yesterday (March 20). The authors urge the research community to drop the concept of statistical significance altogether, and more than 800 statisticians and scientists have signed on to the idea.

Scientists have often misused p-values to make claims about what hypotheses their statistically significant or insignificant results “prove,” leading to hyped claims or artificial conflict between studies, the authors say. Because of the bias in journals towards publishing findings with p-values below 0.05, scientists may ignore interesting results that don’t meet the bar and may pick data or methods to try to surpass the threshold.

The authors say they are not trying to ban p-values. Rather, “we are calling for a stop to the use of P values in the conventional, dichotomous ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Carolyn Wilke

    This person does not yet have a bio.
Share
Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

View this Issue
Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

Element Bioscience Logo
Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
The Scientist Placeholder Image

Seeing and Sorting with Confidence

BD
The Scientist Placeholder Image

Streamlining Microbial Quality Control Testing

MicroQuant™ by ATCC logo

Products

The Scientist Placeholder Image

Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

parse-biosciences-logo

Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies

waters-logo

How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis