Fixing the Flaws in Animal Research
Fixing the Flaws in Animal Research
Many preclinical studies carried out in vivo are poorly designed and generate irreproducible data, but efforts to address the problem are on the rise.
Fixing the Flaws in Animal Research
Fixing the Flaws in Animal Research

Many preclinical studies carried out in vivo are poorly designed and generate irreproducible data, but efforts to address the problem are on the rise.

Many preclinical studies carried out in vivo are poorly designed and generate irreproducible data, but efforts to address the problem are on the rise.

transparency
Opinion: Transparency Is Critical to Defend Animal Research
Opinion: Transparency Is Critical to Defend Animal Research
Cindy Buckmaster | Apr 11, 2019
Research organizations should start sharing with the public information, stories, photos, and videos on how animals are cared for and used in science.
Drop Statistical Significance, Scientists Say
Drop Statistical Significance, Scientists Say
Carolyn Wilke | Mar 21, 2019
In service of an arbitrary threshold, p-values often lead researchers to make poorly supported claims and ignore interesting but insignificant results, scientists argue.
Q&A: John Ioannidis Talks Transparency in Biomedical Literature
Q&A: John Ioannidis Talks Transparency in Biomedical Literature
Shawna Williams | Nov 20, 2018
The Stanford University researcher discusses a new study on measures such as data sharing and funding disclosures.
EPA Postpones Decision on Rule to Restrict Scientific Input
EPA Postpones Decision on Rule to Restrict Scientific Input
Jef Akst | Oct 19, 2018
It will be more than a year before the agency institutes or rejects the controversial changes proposed by former EPA head Scott Pruitt.
Studies Unable to Reproduce Results of Two Diabetes Papers
Studies Unable to Reproduce Results of Two Diabetes Papers
Anna Azvolinsky | Aug 10, 2018
The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.
Effort to Reproduce Cancer Studies Scales Down to 18 Papers
Effort to Reproduce Cancer Studies Scales Down to 18 Papers
Diana Kwon | Aug 1, 2018
The Reproducibility Project: Cancer Biology initially aimed to replicate the results of 50 high-impact research articles.
US Scientists’ Letter Calls for Transparency in Animal Research
US Scientists’ Letter Calls for Transparency in Animal Research
Ashley Yeager | Jun 21, 2018
Nearly 600 signatories, including four Nobel Prize winners, urge openness about animal experiments.
Medical Statistician Doug Altman Dies
Medical Statistician Doug Altman Dies
Kerry Grens | Jun 5, 2018
The cofounder of the EQUATOR Network devoted his career to boosting transparency and improving the quality of clinical research.
EPA Seeks to Restrict the Science Used in Policymaking
EPA Seeks to Restrict the Science Used in Policymaking
Kerry Grens | Apr 23, 2018
Republican politicians have been trying to limit data to only those publicly available, but opponents say that would neglect private, yet important, information.