Epigenetic Marks Tied to Homosexuality

In a small study of male twins, nine methylation sites helped researchers predict a person’s sexual orientation.

Written byKerry Grens
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

PIXABAY, KAZBy examining just a handful of sites along the genome and determining whether they are methylated, scientists can peg sexual orientation with nearly 70 percent accuracy. That’s according to data presented today (October 8) at the American Society of Human Genetics meeting.

“People have been looking for gay genes for 20 years and haven’t been really able to identify them, in spite of the fact that there’s interest,” Sergey Gavrilets, a professor of evolutionary biology at the University of Tennessee in Knoxville who was not involved in the study, told BuzzFeed News. “The existing evidence that we have now does point very strongly towards the significant role of epigenetics in homosexual orientation.”

Gavrilets and a pair of colleagues proposed the idea of epigenetics influencing sexual orientation several years ago. In the latest work, Eric Vilain, a neuroscientist at the University of California, Los Angeles, postdoc Tuk Ngun, and their colleagues scanned through the genomes of 47 male twin pairs. In 37 pairs, one of the brothers was ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

    View Full Profile
Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Golden geometric pattern on a blue background, symbolizing the precision, consistency, and technique essential to effective pipetting.

Best Practices for Precise Pipetting

Integra Logo
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad

Products

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

The Scientist Placeholder Image

Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

OGT logo

OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel