Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

epigenetics
Researchers Analyze Epigenetic Signatures to Diagnose Rare Diseases
Researchers Analyze Epigenetic Signatures to Diagnose Rare Diseases
Katarina Zimmer | Mar 28, 2019
A number of rare diseases show unique epigenetic patterns across the genome, a feature researchers have now exploited to build a diagnostic tool.
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Ashley Yeager | Mar 21, 2019
Certain populations have been historically underrepresented in genome sequencing studies, but the NIH, private clinics, and 23andMe and other companies are trying to fix that.
Ribosomal DNA Can Predict an Animal’s Age
Ribosomal DNA Can Predict an Animal’s Age
Abby Olena | Feb 14, 2019
A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.
Zach Lippman Susses Out How Gene Regulation Affects Plant PhenotypesZach Lippman Susses Out How Gene Regulation Affects Plant Phenotypes
Zach Lippman Susses Out How Gene Regulation Affects Plant Phenotypes
Shawna Williams | Feb 1, 2019
The Cold Spring Harbor Laboratory researcher is fueled by curiosity about how one species’ genome can produce a wide variety of traits.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
Effects of Antidepressants Span Three Generations in Fish
Effects of Antidepressants Span Three Generations in Fish
Diana Kwon | Dec 10, 2018
Fluoxetine dampened stress responses in zebrafish embryos exposed to the drug—and their descendants.
Opinion: The New Frontiers of Epigenetics
Opinion: The New Frontiers of Epigenetics
John D. Loike | Nov 12, 2018
Newly developed techniques could propel a field already advancing rapidly to complement modern medicine.
Infographic: Exercise’s Effects on the Brain
Infographic: Exercise’s Effects on the Brain
Ashley Yeager | Nov 1, 2018
Identifying the molecular interactions that occur all over the body during exercise could reveal how it affects learning and memory.
How Exercise Reprograms the Brain
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.