Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

epigenetics
Technique Talk: Single Cell Sequencing Sample Preparation for Oncology Research
Technique Talk: Single Cell Sequencing Sample Preparation for Oncology Research
The Scientist Creative Services Team in collaboration with 10x Genomics | Apr 29, 2021
In this workshop, learn tips and tricks for preparing cancer tissue samples for a variety of single cell applications.
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Jef Akst | Mar 1, 2021
Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.
<em>The Scientist&nbsp;</em>Speaks Ep. 15 - The Epigenetic Origins of Allergy and Asthma
The Scientist Speaks Ep. 15 - The Epigenetic Origins of Allergy and Asthma
The Scientist Creative Services Team | Feb 26, 2021
Epigenetic marks acquired from environmental exposures throughout life influence human health and may even transcend generations.
Polycystic Ovary Syndrome May Be Inherited Epigenetically
Polycystic Ovary Syndrome May Be Inherited Epigenetically
Katarina Zimmer | Feb 9, 2021
Female mice modeling the hormonal disorder can pass symptoms down for several generations, likely via changes in genome methylation that are similarly observed in women with PCOS.
Genetic Reprogramming Restores Vision in Mice: Study
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
Q&amp;A: How Animals Change in Space
Q&A: How Animals Change in Space
Jef Akst | Nov 25, 2020
Weill Cornell Medicine geneticist Christopher Mason speaks with The Scientist about a bolus of new work on the physiological, cellular, and molecular effects of leaving Earth.
Advances in Nucleic Acid Sequencing
Advances in Nucleic Acid Sequencing
The Scientist Creative Services Team | Aug 13, 2020
Download this eBook to learn how new sequencing methods revolutionize genetics research!
Heart Attack Elevates Risk of Breast Cancer Recurrence: Study
Heart Attack Elevates Risk of Breast Cancer Recurrence: Study
Amanda Heidt | Jul 13, 2020
Mice that experienced heart attacks underwent a large-scale shift in their immune systems that allowed cancer to flourish, perhaps explaining the observation in patients.
Inheriting Memories
Inheriting Memories
The Scientist Staff | Jan 13, 2020
Tel Aviv University neuroscientist Oded Rechavi discusses his studies on the inheritance of acquired traits.
Oded Rechavi Studies the RNA Nematodes Pass to Their Offspring
Oded Rechavi Studies the RNA Nematodes Pass to Their Offspring
Emily Makowski | Jan 13, 2020
The Tel Aviv University researcher is interested in how the macromolecules affect the health and behavior of successive generations of worms.
Early Epigenetic Changes Regulate Voluntary Exercise in Mice: Study
Early Epigenetic Changes Regulate Voluntary Exercise in Mice: Study
Emma Yasinski | Dec 7, 2019
Altering DNA methylation in a particular area of the hypothalamus halved the animals’ voluntary exercise as adults.
Cigall Kadoch Unravels Chromatin&rsquo;s Role in Cancer
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
Worm Parents Pass on Behaviors Epigenetically to Offspring
Worm Parents Pass on Behaviors Epigenetically to Offspring
Katarina Zimmer | Jun 7, 2019
Two research groups demonstrate that in Caenorhabditis elegans, behavioral traits can be passed down through the germline to future generations, even though they aren’t hard-wired.
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Emma Yasinski | Apr 19, 2019
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Researchers Analyze Epigenetic Signatures to Diagnose Rare Diseases
Researchers Analyze Epigenetic Signatures to Diagnose Rare Diseases
Katarina Zimmer | Mar 28, 2019
A number of rare diseases show unique epigenetic patterns across the genome, a feature researchers have now exploited to build a diagnostic tool.
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Ashley Yeager | Mar 21, 2019
Certain populations have been historically underrepresented in genome sequencing studies, but the NIH, private clinics, and 23andMe and other companies are trying to fix that.
Ribosomal DNA Can Predict an Animal&rsquo;s Age
Ribosomal DNA Can Predict an Animal’s Age
Abby Olena | Feb 14, 2019
A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.
Zach Lippman Susses Out How Gene Regulation Affects Plant Phenotypes
Zach Lippman Susses Out How Gene Regulation Affects Plant Phenotypes
Shawna Williams | Feb 1, 2019
The Cold Spring Harbor Laboratory researcher is fueled by curiosity about how one species’ genome can produce a wide variety of traits.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.