Skipping Toward Resistance: The Gradual Adaptation of Cancer Cells
Skipping Toward Resistance: The Gradual Adaptation of Cancer Cells
Instead of an on-off toggle switch, cancer cells adapt through a series of distinct states of increasing drug resistance.
Instead of an on-off toggle switch, cancer cells adapt through a series of distinct states of increasing drug resistance.
epigenetics
Maintaining NK Cells’ Killer Instincts
Aparna Nathan, PhD | Aug 9, 2024 | 4 min read
A protein in natural killer cells keeps them from turning into more docile counterparts.
An Epigenetic Brain Scan
Aparna Nathan, PhD | Jul 16, 2024 | 4 min read
A lower-resolution spatial epigenomics method offers a cost-effective alternative to traditional single-cell approaches.
Exploring the Many Facets of Single Cell Methylation
The Scientist Staff | 1 min read
In this webinar, Austin Holmes and Jason Koth will discuss how to overcome single cell methylation and data analysis hurdles.
Human Neurons Play the Waiting Game
Shelby Bradford, PhD | Jun 5, 2024 | 4 min read
When it comes to development, an epigenetic clock may be responsible for human neurons’ slower maturation.
An Epigenetic Strategy to Control Bad Cholesterol
Maggie Chen | Apr 12, 2024 | 3 min read
Modifying markers on DNA allows scientists to lower cholesterol levels in mice, even long-term.
The Six-Base Genome Reveals Multimodal Data from a Single DNA Sample
The Scientist and biomodal | 4 min read
To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.
Predict Functional Genomics with Confidence
The Scientist Staff | Mar 1, 2024 | 1 min read
An advanced multiomics solution allows researchers to predict gene expression, chromatin accessibility, and enhancer state from one DNA sample.
Epigenetic Changes Drive Cancer
Rebecca Roberts, PhD | Nov 28, 2023 | 3 min read
An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do.
Epigenetics in a Dish
The Scientist | 2 min read
Jonathan Weissman and Luke Gilbert share how they developed several CRISPR-based epigenetic editors and how these tools differ from traditional CRISPR.
Fixing the Problem With Induced Pluripotent Stem Cells
Tanvir Khan, PhD | Oct 31, 2023 | 4 min read
A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman | Sep 25, 2023 | 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
Epigenetic Influences and Mechanisms in Cancer
The Scientist Staff | 1 min read
In this webinar, Özgen Deniz and Christina Leslie will discuss how epigenetic regulation affects oncogenesis.
New Epigenetic Clocks May Confirm Extreme Age
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?
Stress Increases Biological Age, But Recovery Can Revert It
Alejandra Manjarrez, PhD | Apr 21, 2023 | 2 min read
A new study relying on DNA methylation clocks suggests that the biological age of mouse and human cells can fluctuate in response to stressful events.
The Scientist’s Journal Club: Cancer
The Scientist | 1 min read
Scientists present the latest research on immune cell responses to cancer, the role of epigenetics in cancer, and molecular imaging of the tumor microenvironment.
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
Methylation Sequencing in Cancer Detection
The Scientist and Twist Bioscience | 1 min read
Discover how efforts to uncover the genome's methylation patterns advance cancer detection.
Our Favorite Genetics Stories of 2022
Christie Wilcox, PhD | Dec 22, 2022 | 4 min read
This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields.