Mice that Survive Infection Pass on Stronger Immunity
Mice that Survive Infection Pass on Stronger Immunity
Offspring of animals subjected to a real or simulated pathogen were more able to fend off disease, a study finds.
Mice that Survive Infection Pass on Stronger Immunity
Mice that Survive Infection Pass on Stronger Immunity

Offspring of animals subjected to a real or simulated pathogen were more able to fend off disease, a study finds.

Offspring of animals subjected to a real or simulated pathogen were more able to fend off disease, a study finds.

epigenetics
Bianca Jones Marlin Traces How Sensory Inputs Shape the Brain
Bianca Jones Marlin Traces How Sensory Inputs Shape the Brain
Annie Melchor | Oct 1, 2021
The Columbia University neuroscientist researches the biology behind some of our most human experiences, including building family relationships. 
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.
Exercising During Pregnancy Protects Mouse Offspring
Exercising During Pregnancy Protects Mouse Offspring
Jack J. Lee | Aug 1, 2021
Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Jef Akst | Mar 1, 2021
Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.
Polycystic Ovary Syndrome May Be Inherited Epigenetically
Polycystic Ovary Syndrome May Be Inherited Epigenetically
Katarina Zimmer | Feb 9, 2021
Female mice modeling the hormonal disorder can pass symptoms down for several generations, likely via changes in genome methylation that are similarly observed in women with PCOS.
Genetic Reprogramming Restores Vision in Mice: Study
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
Q&A: How Animals Change in Space
Q&A: How Animals Change in Space
Jef Akst | Nov 25, 2020
Weill Cornell Medicine geneticist Christopher Mason speaks with The Scientist about a bolus of new work on the physiological, cellular, and molecular effects of leaving Earth.
Heart Attack Elevates Risk of Breast Cancer Recurrence: Study
Heart Attack Elevates Risk of Breast Cancer Recurrence: Study
Amanda Heidt | Jul 13, 2020
Mice that experienced heart attacks underwent a large-scale shift in their immune systems that allowed cancer to flourish, perhaps explaining the observation in patients.
Inheriting Memories
Inheriting Memories
The Scientist Staff | Jan 13, 2020
Tel Aviv University neuroscientist Oded Rechavi discusses his studies on the inheritance of acquired traits.
Oded Rechavi Studies the RNA Nematodes Pass to Their Offspring
Oded Rechavi Studies the RNA Nematodes Pass to Their Offspring
Emily Makowski | Jan 13, 2020
The Tel Aviv University researcher is interested in how the macromolecules affect the health and behavior of successive generations of worms.