Evidence for Human Lifespan Limit Contested

Five groups of scientists criticize a widely publicized Nature paper from 2016 suggesting that humans can only live up to 115 years.

Written byDiana Kwon
| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

ISTOCK, PRAETORIANPHOTOLast October, a paper published in Nature made a big splash with its claim that human longevity was limited to 115 years. Although the study made headlines in most of the major news outlets, it sparked a heated debate among scientists—not everyone was sold on the authors’ conclusions. Five groups of researchers have now published a series of formal rebuttals that were published today (June 28) in Nature Communications Arising.

In the 2016 study, Jan Vijg, a molecular geneticist at the Albert Einstein College of Medicine, and colleagues analyzed global demographic data over the last century and demonstrated that since the mid-1990s, peak age plateaued at around 115 years. Based on these results, the authors concluded that humans had natural age limit at 115, and that the probability of surviving to over the age of 125 was less than 1 in 10,000.

“It’s an extreme claim that they make that there is a limit to human lifespan, and I think an extreme claim deserves extreme scrutiny,” says Maarten Pieter Rozing, a professor at the University of Copenhagen’s Center for Healthy Aging, who co-authored a rebuttal. “There is an alternative explanation, which is that [maximum age] ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Diana is a freelance science journalist who covers the life sciences, health, and academic life. She’s a regular contributor to The Scientist and her work has appeared in several other publications, including Scientific American, Knowable, and Quanta. Diana was a former intern at The Scientist and she holds a master’s degree in neuroscience from McGill University. She’s currently based in Berlin, Germany.

    View Full Profile
Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research