White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
Different Genes Influence Lifespan in Male and Female Mice
Different Genes Influence Lifespan in Male and Female Mice

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

lifespan
Photo of a clock on a plate with cutlery on either side.
Opinion: Changing When and How Much We Eat May Extend Healthspan
Joseph S. Takahashi and Carla B. Green | Aug 1, 2022
Fasting, eating only at certain times of day, and restricting overall calorie intake can collectively contribute to lifespan extensions in animals. Could the same hold true in humans?
Close-up of the head of the Aldabra Giant Tortoise. Her face is dirty from eating grass on a sandy beach.
How Slow Can You Go?
Hannah Thomasy | Jun 23, 2022
Two studies show negligible rates of aging in some types of turtles and other cold-blooded creatures, but that doesn’t mean they’re immortal.
Illustration of blue shiny mitochondria
Worms Live Longer with Mitochondria Powered by Light: Preprint
Alejandra Manjarrez | May 24, 2022
Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.
Fruit flies in a vial
Accurate Protein Production Promotes Longevity
Ruth Williams | Sep 15, 2021
Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.
A blue coelacanth with white speckles in the ocean
African Coelacanths May Live to Be 100: Study
Catherine Offord | Jun 18, 2021
This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.
Ginkgo’s Extreme Longevity Credited to Immune System
Lisa Winter | Jan 15, 2020
Genes related to the immune system stay active throughout the tree’s life.
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
longevity prediction estimate lifespan methylation telomere biomarkers eldely old age centenarian
Opinion: Biomarkers of Longevity Not Ready for the Clinic
John D. Loike and Ruth L. Fischbach | Sep 27, 2019
The science isn’t there yet, nor are the known interventions that ought to be combined with delivering such predictions.
notebook
An Algorithm to Predict the Age of Your Lab Mice
Anthony King | Feb 1, 2019
Researchers develop an app that can estimate the biological age of a rodent from its mug shot—and could give a boost to the science of human aging in the process.
New Study Questions Whether Death Rate Levels Off in Old Age
Ashley P. Taylor | Dec 21, 2018
A demographer’s model suggests the “mortality plateau” in the extreme elderly could be explained by clerical errors. Not everyone agrees.
Lifespan Less Heritable than Previously Thought
Abby Olena | Nov 6, 2018
Some of the longevity that appears to run in families can instead be attributed to people choosing life partners with similar characteristics.
Risk of Dying Levels Off in Super Old Age: Study
Kerry Grens | Jun 28, 2018
The researchers say that their results are evidence we haven’t yet reached a limit to human lifespan.
Pancreatic Cell Size Negatively Relates to Lifespan in Mammals
Sukanya Charuchandra | Jun 19, 2018
Species with larger pancreatic cells tend to have shorter lives, according to a study.  
Caloric Restriction Slows Signs of Aging in Humans
Diana Kwon | Mar 26, 2018
Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.
13-Million-Person Family Tree Reveals Stories of Human History
Ashley Yeager | Mar 1, 2018
Crowdsourced data from Geni.com, which includes the actor Kevin Bacon, answers questions about marriage, migration, and more.
Could Rapamycin Help Humans Live Longer?
Anne N. Connor | Mar 1, 2018
From extending lifespan to bolstering the immune system, the drug’s effects are only just beginning to be understood.
Mitochondrial Networks Explain Why Caloric Restriction Extends Worms’ Lives
Jef Akst | Nov 7, 2017
Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.
Studies: Ketogenic Mice Live Longer, Healthier Lives
Bob Grant | Sep 5, 2017
High-fat, low-carbohydrate diets are shown to increase lifespan and preserve memory in two independent mouse experiments.
A Potential Remedy for the Aging Brain
Aggie Mika | Aug 8, 2017
In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease.