Genes related to the immune system stay active throughout the tree’s life.

Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.

The science isn’t there yet, nor are the known interventions that ought to be combined with delivering such predictions.

Researchers develop an app that can estimate the biological age of a rodent from its mug shot—and could give a boost to the science of human aging in the process.

A demographer’s model suggests the “mortality plateau” in the extreme elderly could be explained by clerical errors. Not everyone agrees.

Some of the longevity that appears to run in families can instead be attributed to people choosing life partners with similar characteristics.

The researchers say that their results are evidence we haven’t yet reached a limit to human lifespan.

Species with larger pancreatic cells tend to have shorter lives, according to a study.  

Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.

Crowdsourced data from Geni.com, which includes the actor Kevin Bacon, answers questions about marriage, migration, and more.

From extending lifespan to bolstering the immune system, the drug’s effects are only just beginning to be understood.

Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.

High-fat, low-carbohydrate diets are shown to increase lifespan and preserve memory in two independent mouse experiments.

In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 

Food restriction decreases a metabolite that impedes associative learning in worms. 

Five groups of scientists criticize a widely publicized Nature paper from 2016 suggesting that humans can only live up to 115 years.

Greenland sharks can live an estimated 400 years, beating the previous vertebrate longevity record, scientists report.

Signs of getting older are less common among rodents with ramped-up ghrelin production.

Calorie restriction in the organism extends lifespan, supporting a long-standing view that had been challenged by a study published last year.