Photo of Junyue Cao
Junyue Cao Applies Novel Approaches to Aging and Disease
The Rockefeller University geneticist is tracing the full lifespan of individual cells to better understand how and why humans age.
ABOVE: Matthew Septimus, The Rockefeller University
Junyue Cao Applies Novel Approaches to Aging and Disease
Junyue Cao Applies Novel Approaches to Aging and Disease

The Rockefeller University geneticist is tracing the full lifespan of individual cells to better understand how and why humans age.

The Rockefeller University geneticist is tracing the full lifespan of individual cells to better understand how and why humans age.

ABOVE: Matthew Septimus, The Rockefeller University

aging

illustration of human brain
COVID-19 Linked to Neural Changes
Shawna Williams | Mar 7, 2022
A study that examined the brains of people before and after SARS-CoV-2 infection found a decrease in brain volume and damage to olfactory areas compared with controls.
An electron microscopy image of a cell with the nucleolus shown in blue, chromatin in green, and nuclear envelope in red
Aging in Mice Linked to Misexpression of Class of Genes
Sophie Fessl | Dec 21, 2021
Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.
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Fecal Transplant Restores Youth to Old Mice
Roni Dengler, PhD | Aug 30, 2021
Microbiota from young mice reversed some aspects of aging and enhanced brain health in aged mice.
Photograph looking up a tree trunk
Contrary to Common Belief, Some Older Trees Make Fewer Seeds
Annie Melchor | Nov 1, 2021
An analysis of more than half a million trees reveals that many species begin to taper off seed production once they hit a certain size.
man standing in front of gene sequencing machines
Q&A: Nearly Every Single Human Gene Can Be Linked to Cancer
Dan Robitzski | Oct 29, 2021
The Scientist spoke with University of Liverpool aging and longevity researcher João Pedro de Magalhães about how human biases can influence scientific priorities and outcomes in genetics.
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Gut Bugs May Help Centenarians Reach Their 100th Birthdays
Roni Dengler, PhD | Aug 30, 2021
Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness.
Fruit flies in a vial
Accurate Protein Production Promotes Longevity
Ruth Williams | Sep 15, 2021
Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.
Black-and-white headshot of Aubrey de Grey
Aubrey de Grey on Leave After Sexual Harassment Allegations
Jef Akst | Aug 11, 2021
Last night, two women publicly accused the famed anti-aging researcher of inappropriately bringing up sex in the workplace, and they say they are not his only victims.
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Aging and Cancer: A Complex Relationship
The Scientist Creative Services Team | Aug 11, 2021
An expert panel will discuss how aging affects cancer risk, development, and treatment practices.
A blue coelacanth with white speckles in the ocean
African Coelacanths May Live to Be 100: Study
Catherine Offord | Jun 18, 2021
This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.
Dietary Spermidine Boosts Cognition in Insects and Rodents
Ruth Williams | Apr 15, 2021
Mice and flies given the polyamine in their diet have increased brain cell metabolism and cognitive function, and epidemiological data hints at a similar benefit in humans.
The Scientist Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist Creative Services Team | Mar 31, 2021
Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Rachael Moeller Gorman | Apr 1, 2021
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena | Jan 20, 2021
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
RNAi Mechanisms in Neurodegenerative Disease Therapy
The Scientist Creative Services Team | Jun 23, 2020
Experts will explore how RNAi mechanisms can modulate gene expression for the treatment of neurodegenerative diseases and how new methods for their use are being developed. 
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
a patient getting blood drawn for testing
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
Shawna Williams | Nov 2, 2020
The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.
Poor Sleep Linked with Future Amyloid-β Build Up
Abby Olena | Sep 11, 2020
Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.
Male Flies’ Y Chromosome May Contribute to Earlier Deaths
Jef Akst | Jul 13, 2020
As male Drosophila grow old, selfish genetic elements that are abundant on the Y chromosome become more active, which appears to reduce longevity.