A Tweak to Immune Cells Reverses Aging in Mice
A Tweak to Immune Cells Reverses Aging in Mice
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
A Tweak to Immune Cells Reverses Aging in Mice
A Tweak to Immune Cells Reverses Aging in Mice

Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.

Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.

aging
Genetic Reprogramming Restores Vision in Mice: Study
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
Shawna Williams | Nov 2, 2020
The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.
Poor Sleep Linked with Future Amyloid-β Build Up
Poor Sleep Linked with Future Amyloid-β Build Up
Abby Olena | Sep 11, 2020
Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.
Male Flies’ Y Chromosome May Contribute to Earlier Deaths
Male Flies’ Y Chromosome May Contribute to Earlier Deaths
Jef Akst | Jul 13, 2020
As male Drosophila grow old, selfish genetic elements that are abundant on the Y chromosome become more active, which appears to reduce longevity.
Blood Transplants from Active Mice Give Brain Boost to Others
Blood Transplants from Active Mice Give Brain Boost to Others
Lisa Winter | Jul 12, 2020
The researchers behind the results propose that an exercise-induced protein in circulation is responsible for the benefits.
RNAi Mechanisms in Neurodegenerative Disease Therapy
RNAi Mechanisms in Neurodegenerative Disease Therapy
The Scientist Creative Services Team | Jun 23, 2020
Experts will explore how RNAi mechanisms can modulate gene expression for the treatment of neurodegenerative diseases and how new methods for their use are being developed. 
Can Destroying Senescent Cells Treat Age-Related Disease?
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Infographic: How Does Cell Senescence Drive Aging and Disease?
Infographic: How Does Cell Senescence Drive Aging and Disease?
Katarina Zimmer | Mar 1, 2020
The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.
Image of the Day: Old Ovaries
Image of the Day: Old Ovaries
Amy Schleunes | Feb 6, 2020
Oxidative stress associated with aging damages ovarian cells in both humans and nonhuman primates.