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A green and white fish swimming underwater
Rockfish Genes Hold Clues to Human Longevity
By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.
Rockfish Genes Hold Clues to Human Longevity
Rockfish Genes Hold Clues to Human Longevity

By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.

By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.

aging
A younger-looking mouse next to an older-looking one
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist Creative Services Team | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Natalia Mesa, PhD | Sep 29, 2022 | 3 min read
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
A mole-rat poses in the grass 
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats
The Scientist Creative Services Team | 1 min read
Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 
3D rendered images of three T cell
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa, PhD | Sep 16, 2022 | 5 min read
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
Woman holding a glass of water in one hand and pill in the other
Daily Multivitamin May Slow Cognitive Decline in Seniors
Andy Carstens | Sep 14, 2022 | 2 min read
Researchers caution that it’s too soon to recommend supplements based on the results of a new study.
Time Traveling Mini-Brains on a Mission to Conquer Space
Time Traveling Mini-Brains on a Mission to Conquer Space
Iris Kulbatski, PhD | 4 min read
Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.
ant with wings on white background
Secret to Reproductive Ants’ Longevity Revealed
Patience Asanga | Sep 2, 2022 | 3 min read
Researchers say they've figured out how some reproductive ants live up to 30 years—far longer than workers.
LAKSAMEE CAVE
Clinton Cave Investigates How Brain Cells Communicate
Andy Carstens | Sep 1, 2022 | 3 min read
The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | 4 min read
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker | Aug 5, 2022 | 4 min read
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
dark image with red ring
How Immature Egg Cells in Ovaries Resist Aging
Shafaq Zia | Aug 4, 2022 | 3 min read
The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
old dog smiles at camera
Inside the Brains of Aging Dogs
Lesley Evans Ogden, Knowable Magazine | Aug 1, 2022 | 8 min read
In a citizen science project, thousands of pet dogs are helping scientists to understand what happens to memory and cognition in old age.
Close-up of the head of the Aldabra Giant Tortoise. Her face is dirty from eating grass on a sandy beach.
How Slow Can You Go?
Hannah Thomasy | Jun 23, 2022 | 5 min read
Two studies show negligible rates of aging in some types of turtles and other cold-blooded creatures, but that doesn’t mean they’re immortal.
A Rising Star Launches Brain Power into Outer Space
Science Philosophy in a Flash - A Rising Star Launches Brain Power into Outer Space
Iris Kulbatski, PhD | 1 min read
Alysson Muotri shares how tapping into his inner creative spark fuels his pursuit of science.
Artist&rsquo;s rendering of aquamarine T cells in front of a blue and green background.
Study Links Stress to a Faster-Aging Immune System
Margaret Osborne | Jun 21, 2022 | 4 min read
Health data from 5,744 adults over the age of 50 reveals an association between stressors such as discrimination and a relatively small proportion of younger infection-fighting immune cells.
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