African Coelacanths May Live to Be 100: Study
African Coelacanths May Live to Be 100: Study
This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.
African Coelacanths May Live to Be 100: Study
African Coelacanths May Live to Be 100: Study

This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.

This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.

aging
Dietary Spermidine Boosts Cognition in Insects and Rodents
Dietary Spermidine Boosts Cognition in Insects and Rodents
Ruth Williams | Apr 15, 2021
Mice and flies given the polyamine in their diet have increased brain cell metabolism and cognitive function, and epidemiological data hints at a similar benefit in humans.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Rachael Moeller Gorman | Apr 1, 2021
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
<em>The Scientist&nbsp;</em>Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist Creative Services Team | Mar 31, 2021
Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.
A Tweak to Immune Cells Reverses Aging in Mice
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena | Jan 20, 2021
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Genetic Reprogramming Restores Vision in Mice: Study
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
First Alzheimer&rsquo;s Blood Test Rolled Out for Clinical Use in US
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
Shawna Williams | Nov 2, 2020
The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.
Poor Sleep Linked with Future Amyloid-&beta; Build Up
Poor Sleep Linked with Future Amyloid-β Build Up
Abby Olena | Sep 11, 2020
Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.
Male Flies&rsquo; Y Chromosome May Contribute to Earlier Deaths
Male Flies’ Y Chromosome May Contribute to Earlier Deaths
Jef Akst | Jul 13, 2020
As male Drosophila grow old, selfish genetic elements that are abundant on the Y chromosome become more active, which appears to reduce longevity.
Blood Transplants from Active Mice Give Brain Boost to Others
Blood Transplants from Active Mice Give Brain Boost to Others
Lisa Winter | Jul 12, 2020
The researchers behind the results propose that an exercise-induced protein in circulation is responsible for the benefits.
RNAi Mechanisms in Neurodegenerative Disease Therapy
RNAi Mechanisms in Neurodegenerative Disease Therapy
The Scientist Creative Services Team | Jun 23, 2020
Experts will explore how RNAi mechanisms can modulate gene expression for the treatment of neurodegenerative diseases and how new methods for their use are being developed. 
Can Destroying Senescent Cells Treat Age-Related Disease?
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Infographic: How Does Cell Senescence Drive Aging and Disease?
Infographic: How Does Cell Senescence Drive Aging and Disease?
Katarina Zimmer | Mar 1, 2020
The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.
Image of the Day: Old Ovaries
Image of the Day: Old Ovaries
Amy Schleunes | Feb 6, 2020
Oxidative stress associated with aging damages ovarian cells in both humans and nonhuman primates.
Study Finds No Association Between Herpes Virus and Alzheimer&rsquo;s
Study Finds No Association Between Herpes Virus and Alzheimer’s
Katarina Zimmer | Jan 23, 2020
While the findings contradict previous studies that have linked human herpesvirus 6 to the neurodegenerative disease, they do not eliminate the possibility of a relationship.
Ginkgo&rsquo;s Extreme Longevity Credited to Immune System
Ginkgo’s Extreme Longevity Credited to Immune System
Lisa Winter | Jan 15, 2020
Genes related to the immune system stay active throughout the tree’s life.
Increased Neuronal Activity Shortens Lifespan in Animals
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
Metabolic Biomarker &ldquo;Score&rdquo; May Predict Death in Next 5&ndash;10 Years
Metabolic Biomarker “Score” May Predict Death in Next 5–10 Years
Emma Yasinski | Aug 20, 2019
The researchers intend for the tool to eventually help doctors make treatment decisions.
Image of the Day: Alzheimer&rsquo;s Genes
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
Q&amp;A: Organs on a Chip Head to the International Space Station
Q&A: Organs on a Chip Head to the International Space Station
Emma Yasinski | May 1, 2019
Lucie Low, a project leader for Tissue Chips in Space, describes the experiments that are slated to blast off later this week.