aging

A study that examined the brains of people before and after SARS-CoV-2 infection found a decrease in brain volume and damage to olfactory areas compared with controls.

Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.

An analysis of more than half a million trees reveals that many species begin to taper off seed production once they hit a certain size.

The Scientist spoke with University of Liverpool aging and longevity researcher João Pedro de Magalhães about how human biases can influence scientific priorities and outcomes in genetics.

Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.

Last night, two women publicly accused the famed anti-aging researcher of inappropriately bringing up sex in the workplace, and they say they are not his only victims.

This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.

Mice and flies given the polyamine in their diet have increased brain cell metabolism and cognitive function, and epidemiological data hints at a similar benefit in humans.

Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.

Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.

Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.

The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.

Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.

As male Drosophila grow old, selfish genetic elements that are abundant on the Y chromosome become more active, which appears to reduce longevity.