Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.

Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.

Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.

The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.

Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.

As male Drosophila grow old, selfish genetic elements that are abundant on the Y chromosome become more active, which appears to reduce longevity.

The researchers behind the results propose that an exercise-induced protein in circulation is responsible for the benefits.

Experts will explore how RNAi mechanisms can modulate gene expression for the treatment of neurodegenerative diseases and how new methods for their use are being developed. 

A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.