Expedeon AG (Frankfurt: EXN; ISIN: DE000A1RFM03; Prime Standard) announced today it has introduced Lightning-Link® Metal Labeling Kits for use in multiple immunoassay-based applications to support single cell analysis. The new kits will enable users to dramatically enhance the phenotypic analysis of heterogeneous cell populations, providing increased multiplexing capability compared to fluorophore labelling, improving sample throughput and research output.
Metal labeling is a technique using rare metal isotopes as opposed to fluorophores for antibody labeling, distinctly increasing the available analytical spectrum. Because the metals do not produce the background noise associated with fluorophores, multiplexing capabilities are greatly increased. This technique is utilized in numerous fields such as immunology, oncology, phospho-proteomics and haematology through its associated applications, such as dissociation-enhanced lanthanide fluorescence immunoassays, multiplexed ion beam imaging, x-ray fluorescence and mass cytometry (cytometry by time-of-flight).
By using antibodies (or other probes) labeled with purified metal isotopes, mass cytometers can detect more than ...
