First Ancient North American Genome Sequenced

Analysis of 12,600-year-old DNA refutes the idea that Native Americans originated in Western Europe.

Written byAnna Azvolinsky
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Burial siteMIKE WATERSSequencing DNA from the 12,600-year-old skeleton of an infant found in central Montana, scientists have confirmed that early Native Americans descended from ancient Asians, not from Western Europeans, according to a study published in Nature today (February 12). This work, led by ancient DNA expert Eske Willerslev of the University of Copenhagen and his colleagues, marked the first ancient North American genome to have been fully sequenced.

The male infant, “Anzick-1,” who was thought to have been between 12 to 18 months old when he died, was excavated in 1968 from a burial site. His skeleton is the oldest known specimen unearthed in North America belonging to the Clovis people, who populated the continent between 13,000 and 12,600 years ago. The boy was buried alongside 125 ancient artifacts including, antler tools.

Tool remains from the Clovis culture form the most widespread archaeological complex throughout North America. But genetic samples of ancient Americans more than 5,000 years old are rare, making it difficult for scientists to piece together the migration patterns of ancient humans in the New World. For the present study, Willerslev’s team has shown that the infant shared about one-third of ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • head shot of blond woman wearing glasses

    Anna Azvolinsky received a PhD in molecular biology in November 2008 from Princeton University. Her graduate research focused on a genome-wide analyses of genomic integrity and DNA replication. She did a one-year post-doctoral fellowship at Memorial Sloan Kettering Cancer Center in New York City and then left academia to pursue science writing. She has been a freelance science writer since 2012, based in New York City.

    View Full Profile
Share
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Screening 3D Brain Cell Cultures for Drug Discovery

Screening 3D Brain Cell Cultures for Drug Discovery

Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

cytiva logo
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo

Products

The Scientist Placeholder Image

Sino Biological Sets New Industry Standard with ProPure Endotoxin-Free Proteins made in the USA

sartorius-logo

Introducing the iQue 5 HTS Platform: Empowering Scientists  with Unbeatable Speed and Flexibility for High Throughput Screening by Cytometry

parse_logo

Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

shiftbioscience

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery