A tubifer cardinalfish
Genome Spotlight: Tubifer cardinalfish (Siphamia tubifer)
These tiny reef fish harbor luminous bacteria, and the chromosome-level assembly of the species’ genome may facilitate the duo’s use as a vertebrate model for symbiosis.
ABOVE: Tim Wong, California Academy of Sciences
Genome Spotlight: Tubifer cardinalfish (Siphamia tubifer)
Genome Spotlight: Tubifer cardinalfish (Siphamia tubifer)

These tiny reef fish harbor luminous bacteria, and the chromosome-level assembly of the species’ genome may facilitate the duo’s use as a vertebrate model for symbiosis.

These tiny reef fish harbor luminous bacteria, and the chromosome-level assembly of the species’ genome may facilitate the duo’s use as a vertebrate model for symbiosis.

ABOVE: Tim Wong, California Academy of Sciences

sequencing

An illustration depicting pores on a membrane
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
Sophie Fessl | Feb 14, 2022
Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.
Illustration of a DNA-peptide conjugate molecule being pulled through a nanopore in a membrane.
Infographic: Reading Proteins with Nanopores
Sophie Fessl | Feb 14, 2022
Adapting DNA nanopore sequencing to peptides allows researchers to identify single amino acid differences.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist Creative Services Team, Resolve Biosciences | Apr 12, 2022
How to visualize gene expression patterns in situ
A fresh, peeled lychee fruit held above a harvest of fresh lychees
Genome Spotlight: Lychee (Litchi chinensis)
Christie Wilcox | Jan 27, 2022
Whole genome sequences reveal multiple domestications of this agriculturally important tree and may hold the secrets to producing the sweet fruit year round.
orange and blue cell image
Woman’s Body Appears to Rid Itself of HIV
Chloe Tenn | Nov 18, 2021
Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.
Millipore stock
Viral Nucleic Acid Purification in a Single Spin
The Scientist Creative Services Team, MilliporeSigma | Apr 6, 2022
A simple nucleic acid extraction approach quickly purifies genomic viral RNA and DNA while minimizing cross-contamination risks.
Image of the microscopic view of an infectious virus cell, RNA.
Opinion: The Pandemic and the RNA Sequencing Gap
Robert Ross | Sep 1, 2021
RNA sequencing technology lags far behind researchers’ ability to decode and understand DNA. The COVID-19 pandemic has highlighted this dangerous shortcoming.
Opinion: Hunting a Changing Virus
Libusha Kelly | Jul 1, 2021
A broad and nimble sequencing program is necessary to track, anticipate, and quash SARS-CoV-2 and other dangerous pathogens that threaten humanity.
Salmonella living within macrophages can survive antibiotic treatment and potentially give rise to resistance by two different mechanisms that slow or arrest their growth.
Bacteria Go Dormant to Survive Antibiotics and Restart Infections
Niki Spahich, PhD | Mar 7, 2022
In Salmonella, two seemingly similar antibiotic survival strategies result from very different molecular mechanisms.
Q&A: George Church’s Genome Up for Auction
Jef Akst | Apr 19, 2021
A founder of the field of synthetic biology is selling data from his own DNA as a nonfungible token, or NFT, through Nebula Genomics, a personal genome company he cofounded.
2021 life science predictions innovations biotech mrna single-cell sequencing diagnostics
Experts Predict the Hottest Life Science Tech in 2021 and Beyond
Bob Grant | Feb 1, 2021
Last year’s Top 10 Innovations judges look into their crystal balls.
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Revealing Neuronal Influencers Among the Gut Microbiome
The Scientist Creative Services Team | Mar 2, 2022
In this webinar, Sarkis Mazmanian and Daniel Mucida highlight how intestinal bacteria influence neuronal function and regeneration.
coronavirus covid-19 sars-cov-2 genome sequencing africa nigeria
Africa Contributes SARS-CoV-2 Sequencing to COVID-19 Tracking
Munyaradzi Makoni | Mar 30, 2020
In recent years, laboratories on the continent have ramped up genomic sequencing capabilities, offering in-country analyses rather than outsourcing the job.
Most Comprehensive Analysis of Cancer Genomes to Date
Jef Akst | Feb 5, 2020
An interrogation of the whole genomes of more than 2,600 cancers yields clues about the genetic drivers of malignancy, how tumors evolve, and more.
Biomarkers on the Brain: From Sequencing to Functional Imaging
Biomarkers on the Brain: From Sequencing to Functional Imaging
The Scientist Creative Services Team | Nov 16, 2021
An expert panel will discuss biomarker development for brain disorders and considerations for their clinical use.
Ancient Human DNA Provides New Look at African History
Jef Akst | Jan 22, 2020
Genomic information from four children who lived thousands of years ago in what is now Cameroon could shed light on the spread of the Bantu languages and on the history of present-day African populations.
a photo of ampules stored in wire racks
Scripps Acquires Pfizer’s Massive Microbial Library
Jef Akst | Jan 9, 2020
The East Coast campus of the research institute received shipments of freeze-dried or frozen samples of more than 210,000 microbial strains, which scientists plan to mine for potentially useful natural products.
Ancient Secrets of the Plague
The Scientist Speaks - Ancient Secrets of the Plague
Niki Spahich, PhD | Nov 10, 2021
Simon Rasmussen discusses his research tracking the origins of the plague by analyzing ancient DNA.
an illustration of a DNA helix
Clinical Exome Sequencing Tests Are Frequently Incomplete: Study
Kerry Grens | Jan 8, 2020
A review of 36 individuals’ sequencing results performed by three US labs finds thousands of genes that were never fully sequenced to industry standards.