Fish Oil Blocks Chemo

New research suggests that fish fat can prevent chemotherapy drugs from doing their job.

Written byJef Akst
| 1 min read

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Fish oil supplements, which contain omega-3 fatty acids thought to offer a variety of health benefits, can be bad news for cancer patients. According to a study published in Cancer Cell, fish oil can induce resistance to chemotherapy drugs in cancerous cells.

Emile Voest of the University Medical Centre Utrecht and her colleagues found that blood stem cells from mice started producing two fatty acids also found in fish oil, KHT and 16:4(n-3), which somehow enabled tumor cells to evade treatment with the chemotherapy drug cisplatin. Indeed, giving the mice off-the-shelf fish oil supplements had a similar effect. Blocking the production of these fatty acids, on the other hand, improved the effectiveness of the chemotherapy.

"We show that the body itself secretes protective substances into ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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