Genetic Predisposition to Obesity Linked with Depression

The variants associated with the mood disorder included those without metabolic risks, suggesting it is the psychological effects of obesity at play.

Written byAshley P. Taylor
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

ABOVE: © ISTOCK.COM, DEBARARR

People who are obese are more likely to have depression than people who are not, but it’s been unclear how one might cause the other. A study of the relationship between depression and genetic variants linked to higher body mass index published today (November 13) in the International Journal of Epidemiology suggests that obesity causes depression, and that it is the untoward psychological effects related to obesity that drive the mood disorder.

“These new findings are perhaps the strongest so far to suggest higher weights may actually contribute to depression,” Naveed Sattar, a professor of cardiovascular and medical sciences at the University of Glasgow who did not participate in the work, tells The Guardian. “Of course, many other factors can cause depression, but, even so, weight loss might be helpful to improve mental health in some individuals, whereas keeping leaner in general should help lessen chances ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

View this Issue
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo
Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

Element Bioscience Logo
Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
The Scientist Placeholder Image

Seeing and Sorting with Confidence

BD

Products

The Scientist Placeholder Image

Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

agilent-logo

Agilent Announces the Enhanced 8850 Gas Chromatograph

parse-biosciences-logo

Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies