Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease
Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease
Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.
Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease
Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease

Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.

Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.

obesity
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Rachael Moeller Gorman | Apr 1, 2021
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
Q&A: Brown Fat Linked to Better Cardio and Metabolic Health
Q&A: Brown Fat Linked to Better Cardio and Metabolic Health
Amanda Heidt | Jan 12, 2021
Paul Cohen of the Rockefeller University describes his study of thousands of people, finding that the energy-burning tissue is tied to a lower risk of for several diseases, including type 2 diabetes, high blood pressure, and heart disease.
Nearly All NYC-Area COVID-19 Hospitalizations Had Comorbidities
Nearly All NYC-Area COVID-19 Hospitalizations Had Comorbidities
Lisa Winter | Apr 24, 2020
The most common preexisting conditions among the patients were diabetes, obesity, and hypertension.
Image of the Day: 70 Years of Disease Research
Image of the Day: 70 Years of Disease Research
Amy Schleunes | Jan 21, 2020
A video chronicles the course of disease research and prompts questions about where scientists may focus their studies in the future.
Early Epigenetic Changes Regulate Voluntary Exercise in Mice: Study
Early Epigenetic Changes Regulate Voluntary Exercise in Mice: Study
Emma Yasinski | Dec 7, 2019
Altering DNA methylation in a particular area of the hypothalamus halved the animals’ voluntary exercise as adults.
Exercise Changes Our Gut Microbes, But How Isn’t Yet Clear
Exercise Changes Our Gut Microbes, But How Isn’t Yet Clear
Ashley Yeager | Aug 15, 2019
Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.
Laura Bowers Works to Sever the Link Between Obesity and Cancer
Laura Bowers Works to Sever the Link Between Obesity and Cancer
Shawna Williams | Jul 15, 2019
The Purdue University nutrition researcher delves into the details of how fat tissue affects tumors.
Microbe Miner: A Profile of Rob Knight
Microbe Miner: A Profile of Rob Knight
Anna Azvolinsky | Jun 1, 2019
Developing computational tools to analyze the reams of microbial sequencing data his lab generates, the UC San Diego microbiologist is a pioneer of microbiome research.
Genetic Risk Score Developed for Obesity
Genetic Risk Score Developed for Obesity
Kerry Grens | Apr 18, 2019
The tool weighs millions of variants to determine how susceptible a person is to becoming obese.
Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
Catherine Offord | Apr 1, 2019
Researchers disentangle how adipocytes communicate with prostate tumors in mice.
Changes in Height Linked to Increased C-section Rates
Changes in Height Linked to Increased C-section Rates
Abby Olena | Feb 6, 2019
Countries with populations whose average adult height grew late last century are more likely to have high rates of babies delivered surgically.
Genetic Predisposition to Obesity Linked with Depression
Genetic Predisposition to Obesity Linked with Depression
Ashley P. Taylor | Nov 13, 2018
The variants associated with the mood disorder included those without metabolic risks, suggesting it is the psychological effects of obesity at play.
Self-Control Center in the Brain Linked to Weight Loss
Self-Control Center in the Brain Linked to Weight Loss
Ashley P. Taylor | Oct 18, 2018
Activity in the lateral prefrontal cortex was the best correlate of weight loss in a study of people on a restricted-calorie diet.
Maternal Obesity and Diabetes Linked to Autism in Children
Maternal Obesity and Diabetes Linked to Autism in Children
Sukanya Charuchandra | Oct 1, 2018
Inflammation may be a strong contender for the connection between mom’s weight and children’s neurodevelopment, according to lab studies on animals.
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice
Diana Kwon | Sep 10, 2018
The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Abby Olena | Aug 30, 2018
Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.
Researchers Identify Biomarkers for Obesity Risk in Women
Researchers Identify Biomarkers for Obesity Risk in Women
Catherine Offord | May 31, 2018
Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.
Primary Cilia in Neurons Linked to Obesity
Primary Cilia in Neurons Linked to Obesity
Abby Olena | Jan 8, 2018
Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 
Hormone Loss Prevents Obesity and Diabetes in Mice
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.