ISTOCK, GEORGEJASON
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice
The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice

The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.

The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.

obesity
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Abby Olena | Aug 30, 2018
Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.
Researchers Identify Biomarkers for Obesity Risk in Women
Researchers Identify Biomarkers for Obesity Risk in Women
Catherine Offord | May 31, 2018
Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.
Primary Cilia in Neurons Linked to Obesity
Primary Cilia in Neurons Linked to Obesity
Abby Olena | Jan 8, 2018
Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 
Hormone Loss Prevents Obesity and Diabetes in Mice
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.
Why Afternoon Open Heart Surgery Is Better for Patient Outcomes
Why Afternoon Open Heart Surgery Is Better for Patient Outcomes
Catherine Offord | Oct 27, 2017
Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.
A Molecule to Treat Obesity?
A Molecule to Treat Obesity?
Ashley P. Taylor | Oct 18, 2017
GDF-15 lowers body weight in mice and primates.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.
Study: Microglia Tied to Weight Gain in Mice
Study: Microglia Tied to Weight Gain in Mice
Aggie Mika | Jul 5, 2017
Just by activating these immune cells in the brain, scientists could make mice eat more and burn fewer calories.
Running on Empty
Running on Empty
Bob Grant | Jun 1, 2017
Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.