weight

Activity in the lateral prefrontal cortex was the best correlate of weight loss in a study of people on a restricted-calorie diet.

A study of more than 450,000 people finds a certain genetic variant associated with eating more carbs is linked to a thicker waist and higher blood pressure, but less fat.  

New findings suggest that promoting the growth of fiber-loving bacteria may help manage type 2 diabetes.

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

Animals lacking a sense of smell stayed thinner than their smelling counterparts, despite eating the same amount.

Children born to obese parents are at increased risk of failing motor development and cognitive tests, according to an NIH-led study.

Obesity-associated microbiome composition can persist after weight loss, affecting the exchange of metabolites between a mouse and its resident bugs, researchers report.

Post-publication peer review prompts the authors to clarify the ages of mice used in their experiments and share additional data.

Diverting the bile duct around a long stretch of the small intestine could treat obesity without cutting out chunks of the digestive tract.

Gastric bypass surgery can have long-term effects on the composition of the gut microbiome, a small study shows.

Jules Hirsch, who described the link between body weight and metabolism, has died at age 88.

Artificially extended days cause mice to gain fat and alter the function of their brown fat, a study shows.

Losing weight does not mitigate the effects of obesity on tumor development in mice.

Transplanting energy-burning brown fat can prevent excess weight gain in a mouse model of obesity.

A new drug shows promise as a weight-loss solution in mice, prompting the animals to burn calories in the absence of a meal.

Researchers find a new gene connected to obesity in a surprising part of the genome.

When their local team is defeated, people seem to drown their sorrows in saturated fat, but uplifting thinking can change the bad habit.