HIV Returns in “Cured” Child

A Mississippi girl who was thought to have been “functionally cured” of HIV as an infant once again harbors detectable levels of the virus.

Written byJef Akst
| 2 min read

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HIV-infected T cellFLICKR, NIAIDLast March, pediatric HIV specialist Hannah Gay and her colleagues at the University of Mississippi Medical Center made headlines around the world after having essentially eliminated the deadly virus from the body of a baby girl. Now, the researchers have learned, HIV is back—the anti-retroviral combination that had seemed so promising is not a true cure.

“It felt like a punch to the gut,” Gay told reporters this week (July 10). “It was extremely disappointing from both the scientific standpoint . . . but mainly for the sake of the child who is back on medicine and expected to stay on medicine for a very long time,” CNN quoted Gay as saying.

The girl had been born to an HIV-positive mother who received no prenatal care. And with the mother receiving a diagnosis late in her pregnancy, her doctors didn’t have a chance to treat her in an attempt to prevent transmission to the baby. After she was born, the team treated the infant girl with high doses of three antiretroviral drugs, which her mother administered for about a year and ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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