Homo Sapiens Interbred With Denisovans From Two Different Populations

Researchers find that modern human populations carry distinct sets of genes from the extinct hominin species.

Written byShawna Williams
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A replica of a Denisovan finger bone fragment found in a cave in 2008WIKIMEDIA, THILO PARGDenisovans, an ancient hominin species long unknown to science, have yielded another of their secrets: At least two genetically-distinct populations of the species interbred with Homo sapiens, according to a genomics analysis published yesterday (March 15) in Cell.

“This is a breakthrough paper,” David Reich, who studies ancient DNA at Harvard University and did not participate in the study, tells The Washington Post. “It's a definite third interbreeding event,” adding to previously known Denisovan and Neanderthal mixtures, he says.

Denisovans were discovered when a few bones and a tooth from a member of the species were found in a Siberian cave in 2008. Reich and his colleagues later sequenced the DNA found in the bones, compared it to the genomes of other ancient and modern humans, and reported that it belonged to a species distinct from modern humans or Neanderthals. That study also revealed that about 5 percent of the genomes of modern Melanesians, people from the islands of Oceania, derives from Denisovans.

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  • Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor’s degree in biochemistry from Colorado College and a graduate certificate in science communication from the University of California, Santa Cruz. Previously, she worked as a freelance editor and writer, and in the communications offices of several academic research institutions. As news director, Shawna assigned and edited news, opinion, and in-depth feature articles for the website on all aspects of the life sciences. She is based in central Washington State, and is a member of the Northwest Science Writers Association and the National Association of Science Writers.

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