Horizon Discovery Group plc Launches HDx RNA Fusion Reference Standards

Launch of HDx™ FFPE RNA Fusion Reference Standards...

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Horizon Discovery Group plc (LSE: HZD) ("Horizon" or “the Company”), the leading international gene editing company supplying tools and services that power genomics research and the development of personalized medicines today announces the launch of HDx™ FFPE RNA Fusion Reference Standards, independent analytical controls for the optimization and validation of targeted RNA-seq, endpoint RT-PCR or RT-qPCR assays.

This product class is being initially established through the launch of ALK-RET-ROS1 targeted FFPE RNA Fusion Reference Standards. These standards are highly-characterized, biologically-relevant, quality control material used to assess the performance of targeted NGS, RT-PCR and RT-qPCR assays aimed at detecting gene fusions. Each section contains a formalin-fixed, paraffin-embedded (FFPE) cell line multiplex verified to contain EML4-ALK (Variant 1), CCDC6-RET and SLC34A2-ROS1 fusions.

ALK fusions of the genetic markers ALK, RET and ROS1 are found in approximately 3–7% of lung tumors and are an important clinical marker for non-small cell lung cancer. The ...

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