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Horizon Discovery introduces single cell RNAseq-linked CRISPR screening service

  • CRISPR-based screening technology platform to address critical gaps in target ID and validation
  • Single cell RNAseq-linked pooled CRISPR screening offers high-quality screening data and biological insight

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Horizon Discovery Group plc (LSE: HZD) ("Horizon", "the Company", or "the Group"), a global leader in the application of gene editing and gene modulation for cell line engineering, today announced the addition of single cell RNAseq-linked pooled CRISPR screening to its CRISPR screening services portfolio. The platform offers high-quality screening data and biological insight to address critical gaps in target identification and validation.

This launch is the result of a collaboration, announced in 2018, to develop and apply this novel research tool to discover new biology essential for the development of future therapeutics. The biological insight gained from Horizon’s single cell RNAseq-linked CRISPR screening platform could help researchers to gain further understanding into complex biological models and speed up the time from discovery to validation by integrating the effect of gene editing with complex gene expression mapping.

Horizon’s pooled format screens offer researchers access to highly robust whole-genome level analyses ...

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