A traditional fluorescence microscope (left) and high-resolution orientation-independent differential interference contrast microscopy (right) depict heterochromatin (arrows) within the same mouse cell.IMAI ET AL., MOLEC BIO CELL, DOI:10.1091/MBC.E17-06-0359, 2017See R. Imai et al., “Density imaging of heterochromatin in live cells using orientation-independent-DIC microscopy,” Molecular Biology of the Cell, doi:10.1091/mbc.E17-06-
Image of the Day: It’s Alive
New microscopy techniques reveal that heterochromatin—the condensed, seemingly dormant portions of DNA—is not as dense as scientists once thought.

