Infographic: Single-Cell Recordings Identify “Number Neurons”

Some nerve cells in the brains of macaques respond selectively to particular numbers, hinting at a specialized pathway for extracting information about numerical quantity.

Written byCatherine Offord
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In search of the neural pathways that allow the brain to perceive numbers of objects, neuroscientists including Andreas Nieder of the University of Tübin-gen have carried out single-cell recordings in the brains of macaques, among other animals. In a series of experiments, Nieder’s team demonstrated that certain neurons in the intraparietal sulcus (IPS) and the prefrontal cortex (PFC)—parts of the brain that have been implicated in visual attention and higher cognitive processes, respectively—respond selectively to particular quantities of objects. The findings hint at the existence of dedicated “number neurons” that extract numerical information from sensory input. Some researchers propose that these number neurons actually lie downstream of a separate number-extracting system in the visual cortex, while others dispute the idea of a dedicated number-sensing system in the brain at all. More research is needed—in humans as well as in animals—to get to the bottom of how brains perceive and process ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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October 2021

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