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Microscopy image with blue and red neurons, where red indicates neurons involved in a memory engram
Asthma Drug Helps Mice Retrieve Memories “Lost” to Sleep Deprivation
A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.
Asthma Drug Helps Mice Retrieve Memories “Lost” to Sleep Deprivation
Asthma Drug Helps Mice Retrieve Memories “Lost” to Sleep Deprivation

A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.

A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.

brain
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
silhouette of woman's head with lights inside it
Book Excerpt from The Phantom God
John C. Wathey | Jan 2, 2023 | 4 min read
In Chapter 1, “Why Is God Two-Faced?,” author John Wathey argues that the answer to this question is the key to an ethological understanding of religion.
Learn about effective biomarker detection from the blood
Next-Level Neuroscience
The Scientist Creative Services Team and MilliporeSigma | 1 min read
Researchers use Single Molecule Counting (SMC®) technology to probe brain biomarkers.
Book cover of The Phantom God by John C. Wathey
Opinion: Neuroscience Could Help Demystify Religious Experience
John C. Wathey | Jan 2, 2023 | 4 min read
If we ask the right questions, modern tools could help researchers solve mysteries such as why many people believe in a God that both provides unconditional love and levies eternal damnation.
Blue glowing neuron projections
Silent Synapses May Provide Plasticity in Adulthood
Holly Barker | Dec 13, 2022 | 4 min read
Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.
Capturing Brain Complexity in Assembloids 
Capturing Brain Complexity in Assembloids
The Scientist Creative Services Team | 1 min read
In this webinar, Jimena Andersen and Jens Schwamborn will describe the next-generation brain organoids that combine multiple brain regions and cell types in 3D cultures.
This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022
Caught on Camera
The Scientist Staff | Dec 12, 2022 | 4 min read
See some of the coolest images recently featured by The Scientist.
Human hand with white glove holding a white mouse in a green background.
Study Traces a Neural Circuit Behind Green Light–Mediated Pain Relief
Alejandra Manjarrez, PhD | Dec 9, 2022 | 4 min read
A mouse study concludes color-detecting cones in the eye and a subset of neurons in the brain’s thalamus are why green light exposure has an analgesic effect.
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | 4 min read
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
Microglia stained black
Opinion: Harnessing Microglia Cells to Stave Off Neurodegeneration
Kristine Zengeler, The Conversation | Dec 8, 2022 | 5 min read
Dialing up the activity of a protein called SYK in the brain’s “janitors” could provide an avenue to treat Alzheimer’s and other neurodegenerative diseases.
woman entering MRI machine on platform
Researchers Report Decoding Thoughts from fMRI Data
Grace van Deelen | Oct 20, 2022 | 5 min read
A method appears to be the first to noninvasively reconstruct language from brain activity.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
A cross-section of a mouse hypothalamus, where cells of the arcuate nucleus are shown in bright green at the bottom.
Methylation in Young Brains May Be Key to Obesity: Mouse Study
Alejandra Manjarrez, PhD | Oct 19, 2022 | 4 min read
Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study.
Drawing of a mouse scratching itself after watching a video of a different mouse scratching itself.
Specialized Brain Circuit Makes Mice Itchy When They See Others Scratch
Dan Robitzski | Oct 12, 2022 | 4 min read
A previously undetected pathway in the mouse brain bypasses the visual cortex to directly activate contagious itch.
Learn about hot topics in organoid research
Next-Level Organoids
The Scientist Creative Services Team | 1 min read
Researchers use organoid cultures in unique ways to study health and disease.
outline of a brain slice with white patch surrounded by teal
Astrocytes Feed Glioblastoma, Promoting Tumor Growth: Mouse Study
Patience Asanga | Oct 5, 2022 | 3 min read
Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.
Blue Whales - Sri Lanka April 2012
The Evolutionary Shaping of Modern Whales
Connor Lynch | Oct 3, 2022 | 4 min read
A survey of more than 200 whale skulls has unveiled bursts of evolution over the past 50 million years.
The Mosaic Brain
Sejal Davla, PhD | 1 min read
How somatic mutations cause brain diseases
A mouse brain showing activated neurons (white) in the brainstem 3 hours after LPS injection.
Research Pinpoints the Neurons Behind Feeling Sick
James M. Gaines | Sep 23, 2022 | 5 min read
Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds.
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