Irvine Scientific, a worldwide leader in cell culture media development and manufacturing, today announced the introduction of PRIME-XV® T Cell CDM, the first commercially available chemically-defined, animal component-free medium for T cell culture. The new medium has been developed to maximize consistent growth of T cells while maintaining their functionality and therapeutic potential.
An increasingly important trend in cell culture media for gene therapies and immunotherapies is the move away from animal-derived and undefined components to serum-free, animal component-free and chemically-defined culture conditions. When working with T cells the advantage of this is two-fold: animal-derived components are variable between lots; and the naturally occurring cytokines and growth factors in them can result in undesirable effects. For example, cytokines and growth factors have been shown to impact growth, phenotype and the potential of T cells to polarize into therapeutic subtypes. PRIME-XV T Cell CDM removes this variability to provide more consistency ...
