Wetzlar, Germany. Leica Microsystems launches the Fluorescence Recovery After Photobleaching (FRAP) device for widefield microscopy, Leica WF FRAP. The device is made for the investigation of cellular dynamics and provides users the flexibility to define their bleaching area using masks of various sizes and shapes. An addition to the inverted research microscope Leica DMi8, the Leica WF FRAP module includes a built-in 1.4 Watt laser (450 nm) and is controlled via the imaging and analysis software Leica Application Suite X (LAS X). A dedicated application wizard that enables control of all bleaching parameters guides users through their experiments.
Fluorescence Recovery After Photobleaching experiments investigate the characteristics of molecular interactions by selectively bleaching a defined area of a cell and monitoring the recovery kinetics of fluorescent molecules. The Leica WF FRAP module utilizes the Infinity Port, an additional fluorescence port of the inverted research microscope Leica DMi8, so that the laser ...
