Deacetylation
Deacetylation
Edited by: Eugene Russo J. Taunton, C.A. Hassig, S.L. Schreiber, "A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p," Science, 272:408-11, 1996. (Cited in more than 195 papers since publication) Comments by Stuart L. Schreiber, professor of chemistry at Harvard University Stuart Schreiber Vincent G. Allfrey, now a professor emeritus at Rockefeller University, first detected histone deacetylase, or HDAC, activity in nuclear extracts 34 years ago; soon