Interdisciplinary Research
Interdisciplinary Research
These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.A. O'Doherty et al., "An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes," Science, 309:2033–7, Sept. 23, 2005.This is the first study to show that a human chromosome can be introduced into a mouse's germline and transmitted to successive generations. The authors introduced a copy of human chromosome 21. The mice