A number of biotech companies are looking to supplement plant-derived fragrances by engineering bacteria and yeast to produce commercial scents, potentially changing how the industry sources its products.

Plant sources can be unreliable: they are often susceptible to the whims of corrupt governments that can make it difficult to acquire the plants or to natural disasters that lead to supply shortages. Although the ability to produce scents in large quantities is still in development, a number of biotech companies including Allylix, Isobionics, and Evolva, are hoping to create plant-derived scents using engineered microbes.

So far, the only microbe-made fragrances available are the citrus molecules that smell like Valencia oranges and grapefruit peel, as well as vanilla. But companies plan to focus on more rare and difficult-to-acquire smells next. “If you have a rare compound that you can only isolate from a particular orchid that grows in the swamps of Florida,...

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