FLICKR, BOB OWEN
Naked mole rats (Heterocephalus glaber) are sociable, long-lived rodents that have evolved an unusually low sensitivity to some types of pain. In a study published today (October 11) in Cell Reports, researchers have worked out the molecular basis for one type of the rodent’s pain tolerance. A minor amino-acid substitution renders a pain receptor in naked mole rats less responsive, reducing the sensitivity of inflamed tissue to heat.
“We think evolution has selected for this tweak just subtly enough so that the pain signaling becomes non-functional, but not strong enough that it becomes a danger for the animal,” study coauthor Gary Lewin of the Max-Delbruck Center for Molecular Medicine in Berlin, Germany, said in a press release.
In most mammals, a burn causes the affected ...
