National Academies Recommend Field Trials for Gene Drives

A report advises that, although gene-drive modified organisms are not ready to be released, carefully controlled field trials could go ahead.

Written byCatherine Offord
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WIKIMEDIA, AGNOSTICPREACHERSKIDGene drive is a method of stimulating the spread of particular genes through a population, often using CRISPR-based editing technology. In light of the increasing feasibility of deploying such technology, the US National Academies of Sciences, Engineering, and Medicine yesterday (June 8) released a report advising on the responsible use of gene drives. The report’s authors concluded that carefully controlled field trials could proceed, but noted that modified organisms are not yet ready to be released into the environment.

“The potential to reduce human suffering and ecological damage demands scientific attention,” Vanderbilt University’s Elizabeth Heitman, who helped lead the National Academies-appointed committee, told The New York Times. “Gene drive is a fascinating area of science that has promise if we can study it appropriately.”

First conceptualized two years ago, gene drive introduced the tantalizing possibility of eliminating vectors of disease or invasive species. But it also highlighted the issue of regulating organisms in which such changes are known to spread swiftly across populations. Establishing a system of regulation, the report argues, will require an international approach, as gene drives will not observe geopolitical boundaries. The details of this recommendation need fleshing out, noted the Wilson Center’s Todd Kuiken in a statement. “How the U.S. ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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