Neglected Babies Develop Less Myelin

Mice raised in isolation from their mothers developed cognitive deficits similar to those of babies raised in orphanages where physical contact is infrequent.

Written byEdyta Zielinska
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Isolating mouse pups from their mothers early in development can reduce the insulation surrounding neurons of the brain, which leads to problems with memory and socialization, a study in Science reported last week (September 14). The study provides a molecular explanation for the cognitive deficits observed in children raised in orphanages where they are rarely touched.

“This is incredibly important data, because it gives us the neural mechanisms associated with the deleterious changes in the brain” that arise from neglect, Nathan Fox, a cognitive neuroscientist at the University of Maryland told Wired Science.

Researchers from Harvard University took mice that were 21 days old and kept them isolated from other mice for 1 month. Afterwards, they were put in cages with other mice that had been raised with others. Isolated mice spent less time interacting with others, and seemed content inspecting props in the cage. They also performed more poorly ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH