New Role for Leptin: Promoting Synapse Formation in Rat Neurons
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
New Role for Leptin: Promoting Synapse Formation in Rat Neurons

The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.

The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.

neuronal development
Image of the Day: Neuron Guides
Image of the Day: Neuron Guides
Carolyn Wilke | Mar 27, 2019
A gene helps motor neurons successfully venture out from the spinal cord to muscles during mouse development.
Image of the Day: New Neurons
Image of the Day: New Neurons
The Scientist Staff, The Scientist Staff | Mar 28, 2018
Scientists discover a molecular factor that allows them to follow neurons from birth to maturity.
Contributors
Contributors
Jef Akst and Bob Grant | Nov 1, 2017
Meet some of the people featured in the November 2017 issue of The Scientist.
Flickers of Hope
Flickers of Hope
Anna Azvolinsky | Nov 1, 2017
Li-Huei Tsai began her career in cancer biology, then took a fearless leap into neuroscience, making singular breakthroughs along the way.
Advancing Techniques Reveal the Brain’s Impressive Diversity
Advancing Techniques Reveal the Brain’s Impressive Diversity
Sara B. Linker, Fred H. Gage, Tracy A. Bedrosian | Nov 1, 2017
No two neurons are alike. What does that mean for brain function?
Infographic: Understanding Our Diverse Brain
Infographic: Understanding Our Diverse Brain
Fred H. Gage, Tracy A. Bedrosian, Sara B. Linker | Oct 31, 2017
Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.
Image of the Day: Fly Sight
Image of the Day: Fly Sight
The Scientist Staff | Sep 3, 2017
In the developing Drosophila visual system, signals from glia cultivate the growth of neurons from immature cells.
Developing Brains in Dishes
Developing Brains in Dishes
Ashley P. Taylor | Apr 26, 2017
Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures. 
CRISPR-Based Therapy Prevents Retinal Degeneration
CRISPR-Based Therapy Prevents Retinal Degeneration
Anna Azvolinsky | Mar 14, 2017
An experimental treatment sacrifices rod cell function to save cone cells in mice, preventing retinal degeneration, researchers report. 
Nascent Neurons Journey Through Newborn Brain
Nascent Neurons Journey Through Newborn Brain
Anna Azvolinsky | Oct 6, 2016
Young cells make their way to the frontal lobe to create new circuits in the brains of infants, researchers report. 
Identity-Shifting Brain Cells
Identity-Shifting Brain Cells
Ruth Williams | Sep 10, 2015
Cortical interneurons in mice exhibit activity-dependent alterations to their characteristic firing patterns.
Gene Linked to Pain Insensitivity
Gene Linked to Pain Insensitivity
Kerry Grens | May 27, 2015
People with a congenital disorder that makes them unable to feel pain have mutations in a histone-modifying gene. 
Minis Ensure Synaptic Maturation
Minis Ensure Synaptic Maturation
Tracy Vence | May 7, 2014
Once considered neurotransmission-related noise, scientists now show that the spontaneous release of presynaptic vesicles is imperative for the maturation of Drosophila synapses.
Lifelong Neuronal Rebirth
Lifelong Neuronal Rebirth
Kate Yandell | Feb 20, 2014
Neuronal regeneration in the human adult brain is more widespread than previously thought. 
Nascent Neurons Break Free
Nascent Neurons Break Free
Kerry Grens | Jan 9, 2014
Neuronal precursors are partially dismantled during early development before they find their fate.  
An Olfaction Odyssey
An Olfaction Odyssey
Megan Scudellari | Oct 1, 2013
Thanks to a book, a war, and a big green caterpillar, John Hildebrand found himself mapping the exquisite and surprising wiring of the insect olfactory system.
Neurons Live Longer in New Brains
Neurons Live Longer in New Brains
Sabrina Richards | Feb 25, 2013
Transplanting mouse neurons into rats allows the neurons to survive twice as long as they would in mice.
Rita Levi-Montalcini Dies
Rita Levi-Montalcini Dies
Kelly Rae Chi | Jan 1, 2013
The neurophysiologist who earned a Nobel Prize for discovering nerve growth factor has passed away at age 103.
Neglected Babies Develop Less Myelin
Edyta Zielinska | Sep 17, 2012
Mice raised in isolation from their mothers developed cognitive deficits similar to those of babies raised in orphanages where physical contact is infrequent.