Neuro-Insights into Holding It

Scientists reveal the neural underpinnings—and muscles tightly linked with—the involuntary flexing of the pelvic floor, which comprises muscles that help us delay urination.

Written byJef Akst
| 1 min read

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FLICKR, MIKE LICHTResearchers at the University of Southern California (USC) and Loma Linda University incidentally discovered the parts of the brain that control the tightening of the all-important, pee-holding pelvic floor muscles, and identified a number of other muscles throughout the body that flex in concert, according to a study published earlier this month (October 8) in the Journal of Neuroscience.

“We knew that pelvic floor muscles contract involuntarily in healthy people to make sure they don’t accidently urinate, but we didn’t know what part of the nervous system was doing this,” coauthor Jason Kutch, an assistant professor in the Division of Biokinesiology & Physical Therapy at the USC Ostrow School of Dentistry, said in a press release. “Now we know that there are specific brain regions controlling involuntary pelvic floor contraction.”

Kutch and his colleagues were studying chronic abdominal and pelvic floor pain when they discovered the muscular and neural correlates of pelvic floor clenching. Using electromyography (EMG) to measure muscle activation, the team showed tightening in diverse muscles—including the glutes and those in the toes—also results in pelvic floor flexing. Functional MRI further revealed ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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