Next Generation: Nanotube Scaffolds Reconnect Spinal Neurons

A 3-D carbon nanotube mesh enables rat spinal tissue sections to reconnect in culture.

Written byRuth Williams
| 3 min read

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3D carbon nanotube meshJUMMI LAISHRAM The technique: Sections of spinal tissue placed 1 to 2 millimeters apart in a culture dish can reconnect their neurons with the help of an intervening carbon nanotube matrix, according to a study published today (July 15) in Science Advances. The 3-D matrix is also well tolerated when inserted into rat brains, the authors reported.

“The important thing about the paper is that, for the first time, it shows that a three-dimensional scaffold of the carbon nanotubes can really improve the connection between two networks in the spinal cord . . . in comparison with 2-D nanotubes or other 3-D networks,” said neuroscientist Jürg Streit of the University of Bern, Switzerland, who was not involved in the study.

The background: Immediately after a spinal cord injury, “there will be a scar that will physically block any kind of reconnection of the [original] fibers,” explained neurophysiologist Fabio Benfenati of the Italian Institute of Technology in Genova who also did not participate in the study. But researchers believe they might be able to circumvent such lesions. The idea is to induce the ...

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  • ruth williams

    Ruth is a freelance journalist. Before freelancing, Ruth was a news editor for the Journal of Cell Biology in New York and an assistant editor for Nature Reviews Neuroscience in London. Prior to that, she was a bona fide pipette-wielding, test tube–shaking, lab coat–shirking research scientist. She has a PhD in genetics from King’s College London, and was a postdoc in stem cell biology at Imperial College London. Today she lives and writes in Connecticut.

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