Rat Study Points to Role of Uterus in Memory

When researchers removed the reproductive organ, female rats had more difficulty solving a water maze.

Written byCarolyn Wilke
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

ABOVE: © ISTOCK.COM,
NEILLOCKHART

The uterus, often regarded as useless when not carrying a baby, may also play an unforeseen role in memory, researchers studying rats missing the organ reported yesterday (December 6) in Endocrinology.

Heather Bimonte-Nelson and colleagues at Arizona State University removed the reproductive organs of female rats: the uterus, ovaries, both or neither. Six weeks after the operation, the researchers administered a memory test. They sent the rats into a small pool to search for platforms that, while once visible, were now just below the water’s surface.

As compared with the other rats, animals who had only their uterus removed struggled more as the test became increasingly difficult. The scientists also observed differences in the hormone levels of these rats. Overall, the study suggests that signals from the uterus—and not the ovaries, which are better known for their hormone production—influence brain function.

Given that approximately one-third of women ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies