Scientists are banking various samples from recipients of donated uteruses to learn all they can about the biology of the organ, and about transplantation more generally.
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
A combination of approaches, including uterus transplantation and the joining of two animals’ circulatory systems, allowed males to bear pups, according to a preprint. But some experts say the experiments were not justified.
The genes promote the migration of endothelial cells outside of the uterus, a characteristic of both endometriosis and endometrial cancers, a study of mice and human tissue finds.
Less than six months after a woman in Sweden gave birth to a healthy baby from a transplanted womb, doctors in Cleveland begin a clinical trial to test the procedure in 10 US women.