Science Under Glass: Inside a Biosafety Level 4 Lab

Figure 1PANDORA'S BOXESContainment cabinets in a BSL-3 laboratory, prior to the construction of modern BSL-4 labs.At first glance, the lab looks like any other. The refrigerators, centrifuges, and computers are all standard equipment, as are the ubiquitous work hoods. Even the fluorescent lighting and lack of windows are standard issue. It's the coiled air hoses, dangling from the ceiling – and maybe the air-locked, submarine style door that is the lab's only exit – that first betray

| 8 min read

Register for free to listen to this article
Listen with Speechify
0:00
8:00
Share

PANDORA'S BOXES

Containment cabinets in a BSL-3 laboratory, prior to the construction of modern BSL-4 labs.

At first glance, the lab looks like any other. The refrigerators, centrifuges, and computers are all standard equipment, as are the ubiquitous work hoods. Even the fluorescent lighting and lack of windows are standard issue. It's the coiled air hoses, dangling from the ceiling – and maybe the air-locked, submarine style door that is the lab's only exit – that first betrays what goes on inside.

Suspended in the culture media behind that door are biologics whose very names are filled with menace: Ebola, Marburg, and Lassa fever, to name a few. Every day, scientists who work with such pathogens enter an environment unknown to others. Encased in bulky suits, they handle deadly specimens – protected by only a few pairs of gloves – in near isolation. They accept the ponderous equipment and safety ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Amy Adams

    This person does not yet have a bio.

Published In

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome