Stem Cells for Autism?

Scientists express mixed enthusiasm over a trial to use cord blood stem cells as a treatment for autism.

Written byKerry Grens
| 2 min read

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WIKIMEDIA, DOC. RNDR. JOSEF REISCHIG, CSC.Duke University is launching a $41 million stem-cell trial to explore “the use of umbilical cord blood cells to treat autism, stroke, cerebral palsy, and related brain disorders,” according to a press release. While a small, preliminary study involving 20 children is already underway, a prominent scientist in the field is criticizing the trial.

“I think it would be marvelous if this trial worked, but it really seems more like a ‘Hail Mary pass’ than a rational therapy,” Arnold Kriegstein, director of the Broad Center of Regenerative Medicine and Stem Cell Research at the University of California, San Francisco, told the Simons Foundation Autism Research Initiative.

The project, led by Duke’s Joanne Kurtzberg, is based on her research showing that cord blood cells can reduce the signs of brain damage in children with hypoxic ischemic encephalopathy and stimulate neural connectivity in animal models. “The whole program has enormous potential,” she said in the release.

A different stem cell trial for autism has been underway since 2012. “We hope to demonstrate to people [whether] this is worth pursuing or not,” ...

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  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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