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2022 Top 10 Innovations
2022 Top 10 Innovations
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
2022 Top 10 Innovations
2022 Top 10 Innovations

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

cell therapy
Doctors Consider Convalescent T Cell Therapy for COVID-19
Abby Olena, PhD | Nov 6, 2020 | 3 min read
Researchers propose that an infusion of memory T cells from people who have recovered from SARS-CoV-2 infections could treat severe disease.
Are Mesenchymal Stem Cells a Promising Treatment for COVID-19?
Ruth Williams | Apr 9, 2020 | 5 min read
As the first clinical data become available on treating coronavirus patients with the cells, scientists are equivocal about the rationale for the intervention.
Key Strategies for Better Stem Cell Workflows
Solutions for Optimizing Stem Cell Therapy Development
Sartorius | 1 min read
Discover how process knowledge is integral to stem cell workflow improvement and optimization.
car t chimeric antigen receptor t cell immunotherapy pyroptosis cell death perforin macrophage leukemia lymphoma
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Kerry Grens | Jan 20, 2020 | 2 min read
The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.
immune cells t cell natural kill cell cardiac stem cell ipsc
Gene Editing Makes Cells Evade Immune Attack In Vitro
Emma Yasinski | Dec 12, 2019 | 3 min read
To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
Discover how counterflow centrifugation streamlines cell therapy workflows
Closed Cell Processing Systems for Cell Therapy Workflows
Thermo Fisher Scientific | 1 min read
Closed systems increase cell therapy manufacturing process efficiency.
Pelizaeus-Merzbacher disease neural stem cell transplantation
Neural Stem Cell Transplantation Crawls Toward the Clinic
Ashley P. Taylor | Oct 29, 2019 | 9 min read
Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.
gavel fda us stem cell adipose-derived
Judge Says FDA Can Stop Clinic from Selling Stem Cell Treatments
Emma Yasinski | Jun 7, 2019 | 4 min read
The decision may facilitate the agency cracking down more effectively on the unproven interventions these companies sell.
Breaking Down Barriers: Cell Therapy for Solid Tumors
The Persistence of (T Cell) Memory: Towards Cellular Therapy for Solid Tumors
The Scientist Creative Services Team | 1 min read
In this webinar, Douglas Green will describe how early events in T cell activation influence anti-tumor immunity. 
Opinion: Ethical Challenges in Using iPS Cells to Treat Paralysis
John D. Loike and Martin Grumet | Mar 7, 2019 | 3 min read
Uncertainties about the cells’ risk profiles and the potential for hyping unproven therapies mean scientists and the media must tread carefully.
The Biggest Science News of 2018
Kerry Grens | Dec 27, 2018 | 7 min read
From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein
 Learn about analyzing mRNA with direct sequence mapping 
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Journals Retract 13 Papers from Heart Stem Cell Lab
Kerry Grens | Dec 14, 2018 | 1 min read
It’s the latest fallout from an investigation by Harvard and Brigham and Women’s into work overseen by Piero Anversa.
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Katarina Zimmer | Nov 28, 2018 | 6 min read
Since their discovery in 2006, induced pluripotent stem cells have been poised to reprogram regenerative medicine. Twelve years on, here’s how far they’ve come.
Scalable and reproducible solutions in CAR T cell therapy workflows 
Advancing CAR T Cell Research and Development
Bio-Rad | 1 min read
How to develop the best CAR T cell product for preclinical use.
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Ashley P. Taylor | Nov 14, 2018 | 2 min read
This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.
Heart Cell Therapy Trial Paused After Fraud Allegations
Ashley P. Taylor | Oct 30, 2018 | 2 min read
A trial to test whether so-called c-kit cardiac stem cells, first reported by Piero Anversa, could help patients with chronic heart failure has been halted in light of suspicion surrounding his work.
Developing Effective Cell Therapies for Challenging Cancer Types 
Developing Effective Cell Therapies for Challenging Cancer Types
The Scientist Creative Services Team | 1 min read
In this webinar, Sandhya Sharma will discuss how to enrich for antigen-specific T-cells to treat virus-associated malignancies.
Cell and Gene Therapy Tracker: Global CAR T-Cell Trials
The Scientist Staff | Aug 22, 2018 | 1 min read
Investigators have launched numerous clinical trials that test the efficacy of the immunotherapy. Here is a global accounting of these experiments.
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