aneuploidy
Chromosomal Instability Drives Cancer Metastasis
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.
Scientists Destroy Entire Chromosome with CRISPR
Scientists Destroy Entire Chromosome with CRISPR
Kerry Grens | Aug 1, 2017
Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.
Transparency Now
Transparency Now
Mary Beth Aberlin | May 1, 2016
Science is messy. So lay it out, warts and all.
Meiotic Mysteries
Meiotic Mysteries
Karen Schindler | May 1, 2016
Understanding why so many human oocytes contain the wrong number of chromosomes
Picturing Inheritance, 1916
Picturing Inheritance, 1916
Amanda B. Keener | May 1, 2016
This year marks the centennial of Calvin Bridges’s description of nondisjunction as proof that chromosomes are vehicles for inheritance.
Aneuploid Responses
Aneuploid Responses
Catherine Offord | May 1, 2016
A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.
Contributors
Contributors
Catherine Offord, Kerry Grens | May 1, 2016
Meet some of the people featured in the May 2016 issue of The Scientist.
A Scrambled Mess
A Scrambled Mess
Karen Schindler | May 1, 2016
Why do so many human eggs have the wrong number of chromosomes?
AACR Q&A: Angelika Amon
AACR Q&A: Angelika Amon
The Scientist Staff | Apr 19, 2016
The aneuploidy expert shares what she has learned at the American Association for Cancer Research annual meeting.