Optical Genome Mapping Works Well in Detecting Cancer Risk
Optical Genome Mapping Works Well in Detecting Cancer Risk
The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies.
Optical Genome Mapping Works Well in Detecting Cancer Risk
Optical Genome Mapping Works Well in Detecting Cancer Risk

The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies.

The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies.

aneuploidy
Cell Biologist Angelika Amon Dies at 53
Cell Biologist Angelika Amon Dies at 53
Max Kozlov | Nov 4, 2020
A “larger than life personality,” Amon devoted her career to studying the cell cycle and aneuploidy. Her research has shaped the field of cancer biology.
Aneuploidy Could Explain Variability in Female Fertility: Study
Aneuploidy Could Explain Variability in Female Fertility: Study
Catherine Offord | Jan 13, 2020
Eggs from girls and from older women show higher rates of errors in chromosome number.
Unbalanced Chromosomal Inheritance More Common than Thought
Unbalanced Chromosomal Inheritance More Common than Thought
Jef Akst | Oct 11, 2019
A genomic analysis from 23andMe suggests that people inherit two copies of a chromosome from only one parent nearly twice as often as researchers had realized.
Breakthrough Prizes Recognize Aneuploidy Researcher, Biochemist
Breakthrough Prizes Recognize Aneuploidy Researcher, Biochemist
Catherine Offord | Oct 18, 2018
This year’s winners also include the developers of nusinersen, an oligonucleotide therapeutic for spinal muscular atrophy.
Chromosomal Instability Drives Cancer Metastasis
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.
Scientists Destroy Entire Chromosome with CRISPR
Scientists Destroy Entire Chromosome with CRISPR
Kerry Grens | Aug 1, 2017
Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.
Transparency Now
Transparency Now
Mary Beth Aberlin | May 1, 2016
Science is messy. So lay it out, warts and all.
Aneuploid Responses
Aneuploid Responses
Catherine Offord | May 1, 2016
A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.
Picturing Inheritance, 1916
Picturing Inheritance, 1916
Amanda B. Keener | May 1, 2016
This year marks the centennial of Calvin Bridges’s description of nondisjunction as proof that chromosomes are vehicles for inheritance.
Contributors
Contributors
Catherine Offord, Kerry Grens | May 1, 2016
Meet some of the people featured in the May 2016 issue of The Scientist.
A Scrambled Mess
A Scrambled Mess
Karen Schindler | May 1, 2016
Why do so many human eggs have the wrong number of chromosomes?
Meiotic Mysteries
Meiotic Mysteries
Karen Schindler | Apr 30, 2016
Understanding why so many human oocytes contain the wrong number of chromosomes
AACR Q&A: Angelika Amon
AACR Q&A: Angelika Amon
The Scientist Staff | Apr 19, 2016
The aneuploidy expert shares what she has learned at the American Association for Cancer Research annual meeting.
A Benefit of Failed Pregnancy?
A Benefit of Failed Pregnancy?
Ruth Williams | Apr 9, 2015
Scientists find a common genetic variant in mothers that decreases the chance of successful pregnancy.
New DNA-based Prenatal Test
New DNA-based Prenatal Test
Dan Cossins | Mar 1, 2013
Another company has launched a non-invasive DNA screen for genetic disorders in unborn babies, adding to the competition in an emerging market.
Year of the Fetus
Year of the Fetus
Beth Marie Mole | Dec 18, 2012
2012 saw the birth of a handful of non-invasive genetic prenatal tests, but the young industry faces growing pains as legal and ethical questions loom. 
Telomeres in Disease
Rodrigo Calado and Neal Young | May 1, 2012
Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.
Gain a Chromosome and Adapt
Sabrina Richards | Jan 29, 2012
Research in yeast shows that aneuploidy is both a consequence of and an adaptation to stress.