ADVERTISEMENT
ADVERTISEMENT
bace1 alzheimer's disease gga3 axon neuron
Alzheimer’s-Linked Mutation Causes Blockages in Neurons
The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.
Alzheimer’s-Linked Mutation Causes Blockages in Neurons
Alzheimer’s-Linked Mutation Causes Blockages in Neurons

The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.

The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.

axon
Accurately measure a neurodegeneration biomarker from blood samples
Detecting an Accessible Biomarker of Neurodegeneration
ProteinSimple, a Bio-Techne brand | Nov 4, 2021 | 1 min read
A sensitive, automated immunoassay measures neurofilament light from patient blood samples.
Non-Concussive Head Hits Influence the Brain’s Microstructure
Lisa Winter | Oct 1, 2020 | 2 min read
Comparing the brain scans of high-impact rugby players with those of athletes in noncontact sports, such as rowing and swimming, revealed tiny, yet significant, differences in the brain’s white matter.
Stem Cell Implants Improve Monkeys’ Grip After Spinal Cord Injury
Ashley Yeager | Feb 26, 2018 | 3 min read
Thousands of axons grew from the transplants and connected to damaged primate tissue, the first such demonstration in primates.
Neural Connectome Method Uses mRNA Barcodes
Ruth Williams | Nov 1, 2016 | 3 min read
Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.
 
Genetic Tags Illuminate Where Neurons Extend
Ruth Williams | Oct 31, 2016 | 1 min read
Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.
The First Neuron Drawings, 1870s
Amanda B. Keener | Oct 1, 2015 | 3 min read
Camillo Golgi’s black reaction revealed, for the first time, the fine structures of intact neurons, which he captured with ink and paper.
Mitochondria Munchers
Jyoti Madhusoodanan | Nov 1, 2014 | 2 min read
Glial cells consume mitochondria released by neurons in the optic nerve.
ADVERTISEMENT