The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.

Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

Pancreatic cells engineered to produce insulin did not immediately provoke an immune response.

A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.

Scientists have constructed three-dimensional maps depicting the size and location of insulin-producing islet cells in the mouse pancreas.

The diabetic volunteer continued to produce insulin one year after she received a transplant of abdominal islet cells.

The results, which could not be replicated, suggested that a hormone increased pancreatic β cell proliferation, supplanting insulin as a front-line diabetes treatment in mice.

Lipids and insulin play important roles in blood sugar regulation, and altered levels of either could kick start metabolic dysfunction.

Scientists grow gastric organs in vitro that can restore insulin production when transplanted into mice.