Studies Unable to Reproduce Results of Two Diabetes Papers
Studies Unable to Reproduce Results of Two Diabetes Papers
The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.
Studies Unable to Reproduce Results of Two Diabetes Papers
Studies Unable to Reproduce Results of Two Diabetes Papers

The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.

The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.

beta cells
Reprogrammed Cells Treat Diabetes in Mice
Reprogrammed Cells Treat Diabetes in Mice
Abby Olena | May 2, 2018
Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.
Gene Therapy Temporarily Reverses Type 1 Diabetes in Mice
Gene Therapy Temporarily Reverses Type 1 Diabetes in Mice
Shawna Williams | Jan 4, 2018
Pancreatic cells engineered to produce insulin did not immediately provoke an immune response.
Immunotherapy Promising for Diabetes: Study
Immunotherapy Promising for Diabetes: Study
Aggie Mika | Aug 9, 2017
A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.
Image of the Day: Over the Islet Rainbow
Image of the Day: Over the Islet Rainbow
The Scientist Staff | Jun 13, 2017
Scientists have constructed three-dimensional maps depicting the size and location of insulin-producing islet cells in the mouse pancreas.
Bioengineered ‘Pancreas’ Effective in First Patient
Bioengineered ‘Pancreas’ Effective in First Patient
Aggie Mika | May 12, 2017
The diabetic volunteer continued to produce insulin one year after she received a transplant of abdominal islet cells.
High-Profile Diabetes Study Retracted
High-Profile Diabetes Study Retracted
Joshua A. Krisch | Dec 28, 2016
The results, which could not be replicated, suggested that a hormone increased pancreatic β cell proliferation, supplanting insulin as a front-line diabetes treatment in mice.
How High Fat and Insulin Levels May Lead to Diabetes
How High Fat and Insulin Levels May Lead to Diabetes
Barbara E. Corkey | Jun 30, 2016
Lipids and insulin play important roles in blood sugar regulation, and altered levels of either could kick start metabolic dysfunction.
Insulin-Producing Mini Stomachs
Insulin-Producing Mini Stomachs
Catherine Offord | Feb 22, 2016
Scientists grow gastric organs in vitro that can restore insulin production when transplanted into mice.
Diabetes “Breakthrough” Breaks Up
Diabetes “Breakthrough” Breaks Up
Kerry Grens | Oct 27, 2014
A hormone thought to make murine insulin-secreting cells proliferate in mice did not perform in replication studies.