Skip to main content

Diabetes Linked to Malnutrition Is Metabolically Unique: Study

Results from a small sample of Indian males suggest that lean individuals with a history of malnutrition suffer from a distinct type of diabetes characterized by a defect in insulin secretion.

Written byAlejandra Manjarrez, PhD
| 5 min read
Micrograph of a beta cell, where insulin granules are shown as blue small balls, mitochondria are colored green, and a fraction of the cell nucleus appears in purple.
Register for free to listen to this article
Listen with Speechify
0:00
5:00

Between the 1950s and 1980s, various studies reported the prevalence of diabetes with distinctive features in young people with a history of nutritional deficiency in low- and middle-income countries. The reports motivated the World Health Organization (WHO) to create the category “malnutrition-related diabetes mellitus.” But in 1999, the same agency removed it as an official category, based on what it said was a lack of evidence “that diabetes can be caused by malnutrition or protein deficiency per se.”

A clinical study published May 27 in Diabetes Care now argues that malnutrition-related diabetes mellitus is indeed a distinct type of diabetes, and that studying it as such may improve how it is treated. By studying a small sample of diabetic and healthy males from South India, the authors concluded that diabetic patients with a body mass index (BMI) of 19 kg/m2 or below with a history of malnutrition have a defect ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • alejandra manjarrez

    Alejandra Manjarrez is a freelance science journalist who contributes to The Scientist. She has a PhD in systems biology from ETH Zurich and a master’s in molecular biology from Utrecht University. After years studying bacteria in a lab, she now spends most of her days reading, writing, and hunting science stories, either while traveling or visiting random libraries around the world. Her work has also appeared in Hakai, The Atlantic, and Lab Times.

    View Full Profile

Related Topics

Related articles background image
August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

View this Issue
Improving rAAV Production for Viral Vector Manufacturing

Improving rAAV Production for Viral Vector Manufacturing

cytiva logo
Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Scientist holding a clear 384-well PCR microplate in a laboratory

What Dictates PCR Success Before Amplification Begins?

Integra Logo
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems

Products

Sino Biological Logo

Sino Biological Launches European Newsletter Campaign with Exclusive Welcome Gifts

Sino Biological Logo

Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

Sino Biological Logo

Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo